Iashchuk E V
Genetika. 1985 Nov;21(11):1909-17.
A hypothesis claiming that the total phenotypes of finger patterns are controlled by three independent two-allele loci A, L and W with the complete dominance in each was analysed in this work. By means of the population genetics methods, non-accordance of the hypothesis examined to the observed distributions of total phenotypes A, L, W, AL, LW, ALW was revealed on the material of five populations (3060 men). On the basis of the segregation analysis method applied to 210 complete families (the total number of children-532), the hypothesis of one-locus heredity with the complete dominance of total phenotypes A and W was rejected, the reliability of this conclusion being 0.999 and 0.95, respectively. The hypothesis of the L pattern being genetically controlled by one locus with the complete dominance gave, when examined, the contradictory results, due to monomorphism of the character.
本研究分析了一个假说，该假说认为手指纹路的总表型由三个独立的双等位基因位点A、L和W控制，每个位点均表现为完全显性。通过群体遗传学方法，在五个群体（3060名男性）的材料中发现，所检验的假说与观察到的总表型A、L、W、AL、LW、ALW的分布不一致。基于对210个完整家庭（子女总数为532）应用的分离分析方法，总表型A和W完全显性的单基因遗传假说被拒绝，该结论的可靠性分别为0.999和0.95。由于性状的单态性，L型由一个完全显性位点进行遗传控制的假说在检验时给出了相互矛盾的结果。
