Saki Forough, Ranjbar Omrani Gholamhossein, Jeddi Marjan, Bakhshaieshkaram Marzie, Dabbaghmanesh Mohammad Hossein
Shiraz Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Endocrine and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Int J Endocrinol Metab. 2017 Jul 26;15(4):e14099. doi: 10.5812/ijem.14099. eCollection 2017 Oct.
Improving peak bone mass and bone strength in the first years of life and enhancing it during young adulthood could prevent osteoporosis and fractures in the last years of life. We evaluated the prevalence of low bone mass in the lumbar and femoral neck and its associated factors in southern Iranian children.
This is a cross-sectional study on healthy Iranian children aged 9 - 18 years old during 2011 - 2012. Dual energy X-ray absorptiometry (DEXA) was used for measuring bone mineral density (BMD). BMD Z-score ≤ -2 was considered as low. Anthropometric data, physical activity, sun exposure, puberty, and mineral biochemical parameters were assessed. Data were analyzed using SPSS v.15.
477 normal children, including 236 (49.5%) girls and 241 (50.5%) boys, aged 13.8 ± 2.7 years were enrolled. Prevalence of low bone mass (LBM) in the femoral and lumbar region was 10.7% and 18.7%, respectively. The prevalence of LBM in femur of girls is twice more than boys. Fat mass index, BMI Z-score, and physical activity were associated with lumbar low bone mass. BMI Z-score and physical activity were associated with femoral low bone mass.
High prevalence of low bone mineral density in children 9 to 18 years in south of the country is concerned and is needed to plan for prevention and treatment. BMI-Z score, fat mass index, and physical activity were the 3 most important preventive factors in developing low bone mass in children.
在生命的最初几年提高峰值骨量和骨强度，并在成年早期增强骨量，可预防生命后期的骨质疏松症和骨折。我们评估了伊朗南部儿童腰椎和股骨颈低骨量的患病率及其相关因素。
这是一项针对2011 - 2012年间9至18岁健康伊朗儿童的横断面研究。采用双能X线吸收法（DEXA）测量骨密度（BMD）。BMD Z评分≤ -2被视为低骨量。评估人体测量数据、身体活动、日照、青春期和矿物质生化参数。使用SPSS v.15分析数据。
纳入了477名正常儿童，包括236名（49.5%）女孩和241名（50.5%）男孩，年龄为13.8 ± 2.7岁。股骨和腰椎区域低骨量（LBM）的患病率分别为10.7%和18.7%。女孩股骨低骨量的患病率是男孩的两倍。脂肪量指数、BMI Z评分和身体活动与腰椎低骨量有关。BMI Z评分和身体活动与股骨低骨量有关。
该国南部9至18岁儿童低骨密度的高患病率令人担忧，需要制定预防和治疗计划。BMI-Z评分、脂肪量指数和身体活动是儿童发生低骨量的3个最重要的预防因素。
