Mustafi Debarshi, Damato Bertil, Berry Jesse L
Department of Ophthalmology, USC Roski Eye Institute and Children's Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Los Angeles, CA.
Ocular Oncology Service, University of California, San Francisco, CA, USA.
Ocul Oncol Pathol. 2017 Dec;4(1):48-51. doi: 10.1159/000478102. Epub 2017 Jul 19.
We report a case of multifocal choroidal melanoma in the same eye, separated in presentation by 20 years. A 57-year-old Caucasian male initially presented with a choroidal melanoma of the right eye that was treated with transpupillary thermotherapy. Due to recurrence, the patient underwent proton beam therapy with subsequent tumor regression. A second small choroidal lesion was noted in the right eye during his surveillance examinations that was closely monitored and demonstrated stable dimensions and features suggestive of a choroidal nevus. Twenty years after his first presentation, the second lesion exhibited accelerated growth with imaging studies indicative of transformation to a distinct choroidal melanoma. The patient underwent a second globe salvage treatment of proton beam therapy. We describe the clinical course, radiographic, and imaging findings of this rare choroidal melanoma.
我们报告了一例同一只眼睛中出现多灶性脉络膜黑色素瘤的病例，两次发病间隔20年。一名57岁的白种男性最初因右眼脉络膜黑色素瘤接受了经瞳孔温热疗法。由于复发，该患者接受了质子束治疗，随后肿瘤消退。在随访检查中，右眼发现了第二个小的脉络膜病变，该病变受到密切监测，其大小稳定，特征提示为脉络膜痣。首次发病20年后，第二个病变出现加速生长，影像学检查表明已转变为明显的脉络膜黑色素瘤。该患者接受了第二次挽救眼球的质子束治疗。我们描述了这种罕见的脉络膜黑色素瘤的临床过程、影像学和成像结果。
