Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China.
Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China.
Mol Med Rep. 2018 Mar;17(3):4460-4466. doi: 10.3892/mmr.2018.8431. Epub 2018 Jan 15.
The present study aimed to investigate the technical feasibility and initial clinical outcomes of a covered stent for the endovascular treatment of superficial femoral artery (SFA) pseudoaneurysm in drug abusers. A total of 29 drug abuse patients with SFA pseudoaneurysm, as confirmed by color Doppler sonography, were enrolled to the present study between January 2012 and May 2014. All patients were treated percutaneously by implantation of a covered stent. Physical examination and lower extremity computed tomography angiography were performed at 1 and 9 months postoperation. Furthermore, the ankle‑brachial index (ABI) of all patients was measured. The results indicated that placement of the covered stent was technically successful in all 29 patients. All of the ruptured pseudoaneurysms were successfully sealed with no cases of intraprocedural mortality. In addition, all patients' conditions improved rapidly; active hemorrhage subsidence and vascular bruit disappearance were immediately detected following implantation of the covered stent. During the follow‑up period, pain was markedly alleviated and pulsatile mass was decreased as time increased. No complaints or complications were documented. A total of 9 months postoperation, pain and pulsatile mass were not detected. The patency rate of the stent was 100%, and no migration, occlusion or infection was detected. In addition, the ABI was significantly improved, from 0.52±0.09 to 0.97±0.37 (P<0.01). In conclusion, the placement of a covered stent may be considered a promising approach to provide an effective, safe and minimally invasive option for the treatment of SFA pseudoaneurysm in drug abusers.
本研究旨在探讨带膜支架腔内治疗药物滥用患者股浅动脉假性动脉瘤的技术可行性和初步临床结果。2012 年 1 月至 2014 年 5 月,共有 29 例经彩色多普勒超声证实的股浅动脉假性动脉瘤药物滥用患者纳入本研究。所有患者均采用带膜支架植入经皮治疗。术后 1 个月和 9 个月进行体格检查和下肢 CT 血管造影,所有患者均测量踝肱指数(ABI)。结果表明,29 例患者均成功实施带膜支架置入术。所有破裂的假性动脉瘤均被成功封堵,无术中死亡病例。此外,所有患者的病情迅速改善;植入带膜支架后,立即发现活动性出血消退和血管杂音消失。随访期间,随时间推移,疼痛明显减轻,搏动性肿块减小。无投诉或并发症记录。术后 9 个月,未发现疼痛和搏动性肿块。支架通畅率为 100%,无支架移位、闭塞或感染。此外,ABI 明显改善,从 0.52±0.09 增加到 0.97±0.37(P<0.01)。综上所述,带膜支架置入术可能是一种有前途的方法,可为药物滥用患者股浅动脉假性动脉瘤的治疗提供有效、安全和微创的选择。