The Blackett Laboratory, Imperial College London, London SW7 2AZ, United Kingdom.
Division of Research, Kaiser Permanente Northern California, Oakland, California 94612, USA.
Phys Rev E. 2017 Oct;96(4-1):040401. doi: 10.1103/PhysRevE.96.040401. Epub 2017 Oct 2.
The networks of veins and arteries on the chorionic plate of the human placenta are analyzed in terms of Voronoi cells derived from these networks. Two groups of placentas from the United States are studied: a population cohort with no prescreening, and a cohort from newborns with an elevated risk of developing autistic spectrum disorder. Scaled distributions of the Voronoi cell areas in the two cohorts collapse onto a single distribution, indicating common mechanisms for the formation of the complete vasculatures, but which have different levels of activity in the two cohorts.
人类胎盘绒毛板上的静脉和动脉网络,根据源自这些网络的 Voronoi 细胞进行分析。研究了来自美国的两组胎盘:一组是没有预先筛选的人群队列,另一组是来自新生儿的队列,他们有发展出自闭症谱系障碍的高风险。两个队列的 Voronoi 细胞面积的比例分布都可以归结为单个分布,这表明完整血管形成的机制相同,但在两个队列中其活性水平不同。