Alessandrino Francesco, Shah Hina J, Ramaiya Nikhil H
Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Clin Imaging. 2018 Jul-Aug;50:96-103. doi: 10.1016/j.clinimag.2017.12.014. Epub 2018 Jan 9.
Immune-related endocrine adverse events occur in up to one third of patients treated with immune checkpoint inhibitors. The purpose of this article is to provide a comprehensive review of the multimodality imaging features of the different immune-related endocrine adverse events. In this article, we will introduce the different types of immune checkpoint inhibitors used in clinical practice, and for each endocrine organ affected we will describe the clinical presentation, the multimodality imaging features at presentation and after treatment, and the possible differential diagnosis.
接受免疫检查点抑制剂治疗的患者中，高达三分之一会发生免疫相关内分泌不良事件。本文旨在全面综述不同免疫相关内分泌不良事件的多模态影像学特征。在本文中，我们将介绍临床实践中使用的不同类型免疫检查点抑制剂，对于每个受影响的内分泌器官，我们将描述其临床表现、就诊时及治疗后的多模态影像学特征，以及可能的鉴别诊断。
