Haouzi Annick, Ahmed Ahmed
Heart and Vascular Institute, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.
Department of Cardiology, St Bernards Heart and Vascular, Jonesboro, Arkansas, USA.
BMJ Case Rep. 2018 Jan 17;2018:bcr-2017-222114. doi: 10.1136/bcr-2017-222114.
A 51-year-old man presented with chest pain, high troponin level, inflammatory syndrome and ST-segment elevation in the anterior leads. While the transthoracic echocardiogram (TTE) showed anteroseptal hypokinesis and apical akinesis, the coronary angiogram was normal. Cardiac MR demonstrated a typical aspect of myocarditis (multiple areas of mid-myocardial late gadolinium enhancement, sparing the subendocardial layer, along with oedema). The initial diagnosis was clinically suspected myocarditis with pseudoinfarct presentation. However, the short-term evolution was not typical of this syndrome, since an apical transmural scar with aneurysm developed within 2 weeks. Seven years later, the patient remained asymptomatic, while Q waves persisted in anterior leads along with an apical aneurysm on TTE. A transmural myocardial necrosis with aneurysm is an unusual complication of acute myocarditis. The potential mechanisms accounting for the development of these lesions are reviewed, and the clinical implications for the diagnosis and monitoring of acute myocarditis are discussed.
一名51岁男性因胸痛、肌钙蛋白水平升高、炎症综合征及前壁导联ST段抬高就诊。经胸超声心动图(TTE)显示前间隔运动减弱及心尖运动消失,而冠状动脉造影正常。心脏磁共振成像显示心肌炎的典型表现(心肌中层多个晚期钆增强区域,不累及心内膜下层,伴有水肿)。初步诊断临床怀疑为伴有假性梗死表现的心肌炎。然而,短期病情演变并非该综合征的典型表现,因为在2周内出现了伴有动脉瘤的心尖透壁性瘢痕。7年后,患者仍无症状,而前壁导联Q波持续存在,TTE显示有心尖动脉瘤。透壁性心肌坏死伴动脉瘤是急性心肌炎的一种不寻常并发症。本文回顾了这些病变发生发展的潜在机制,并讨论了其对急性心肌炎诊断和监测的临床意义。