Nakatomi Yasuhito, Kuratsune Hirohiko, Watanabe Yasuyoshi
Nakatomi Fatigue Care Clinic.
Brain Nerve. 2018 Jan;70(1):19-25. doi: 10.11477/mf.1416200945.
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by chronic, profound, disabling, and unexplained fatigue; cognitive impairment; and chronic widespread pain. By using positron emission tomography, our study demonstrated neuroinflammation in the brain of patients with ME/CFS. Neuroinflammation was found to be widespread in the brain areas of the patients with ME/CFS and was associated with the severity of their neuropsychological symptoms. The ongoing research would lead to the establishment of objective diagnostic criteria and development of an appropriate therapy.
肌痛性脑脊髓炎/慢性疲劳综合征（ME/CFS）的特征为慢性、严重、致残且无法解释的疲劳；认知障碍；以及慢性广泛性疼痛。通过正电子发射断层扫描，我们的研究证明了ME/CFS患者大脑中存在神经炎症。研究发现神经炎症在ME/CFS患者的脑区广泛存在，并且与他们神经心理症状的严重程度相关。正在进行的研究将导致建立客观的诊断标准并开发出合适的治疗方法。
