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Motor neuron disease in 2017: Progress towards therapy in motor neuron disease.

作者信息

Kiernan Matthew C

机构信息

Brain and Mind Centre, University of Sydney, New South Wales 2040, Australia.

出版信息

Nat Rev Neurol. 2018 Feb;14(2):65-66. doi: 10.1038/nrneurol.2017.186. Epub 2018 Jan 19.

DOI:10.1038/nrneurol.2017.186
PMID:29348545
Abstract
摘要

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Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy.依库珠单抗治疗婴儿型脊髓性肌萎缩症的疗效观察
N Engl J Med. 2017 Nov 2;377(18):1723-1732. doi: 10.1056/NEJMoa1702752.
2
Monitoring disease progression with plasma creatinine in amyotrophic lateral sclerosis clinical trials.在肌萎缩侧索硬化症临床试验中用血浆肌酸酐监测疾病进展。
J Neurol Neurosurg Psychiatry. 2018 Feb;89(2):156-161. doi: 10.1136/jnnp-2017-317077. Epub 2017 Oct 30.
3
Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials.
TDP-43、内源性逆转录病毒与肌萎缩性侧索硬化症炎症性神经变性的分子联系:抗逆转录病毒疗法特鲁瓦达(Triumeq)的潜在靶点。
Mol Neurobiol. 2023 Nov;60(11):6330-6345. doi: 10.1007/s12035-023-03472-y. Epub 2023 Jul 14.
4
A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?肌萎缩侧索硬化症治疗方法的展望:疾病进展能否得到遏制?
Transl Neurodegener. 2021 Aug 10;10(1):29. doi: 10.1186/s40035-021-00250-5.
5
Risk Factors and Emerging Therapies in Amyotrophic Lateral Sclerosis.肌萎缩侧索硬化症的风险因素和新兴疗法。
Int J Mol Sci. 2019 May 28;20(11):2616. doi: 10.3390/ijms20112616.
6
Machine Learning in Amyotrophic Lateral Sclerosis: Achievements, Pitfalls, and Future Directions.肌萎缩侧索硬化症中的机器学习:成就、陷阱与未来方向。
Front Neurosci. 2019 Feb 28;13:135. doi: 10.3389/fnins.2019.00135. eCollection 2019.
7
Microhexagon gradient array directs spatial diversification of spinal motor neurons.微六边体梯度阵列指导脊髓运动神经元的空间多样化。
Theranostics. 2019 Jan 1;9(2):311-323. doi: 10.7150/thno.29755. eCollection 2019.
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Interaction of Half Oxa-/Half -Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity.半氧杂/半铂配合物与人超氧化物歧化酶的相互作用及神经毒性的诱导降低
ACS Med Chem Lett. 2018 Oct 1;9(11):1094-1098. doi: 10.1021/acsmedchemlett.8b00199. eCollection 2018 Nov 8.
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Geographic Analysis of Motor Neuron Disease Mortality and Heavy Metals Released to Rivers in Spain.地理分析西班牙河流中释放的重金属与运动神经元病死亡率的关系。
Int J Environ Res Public Health. 2018 Nov 11;15(11):2522. doi: 10.3390/ijerph15112522.
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Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS.肥大细胞和中性粒细胞介导 ALS 的周围运动通路变性。
JCI Insight. 2018 Oct 4;3(19):123249. doi: 10.1172/jci.insight.123249.
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Neurology. 2017 Oct 31;89(18):1915-1922. doi: 10.1212/WNL.0000000000004606. Epub 2017 Oct 4.
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J Neurol Neurosurg Psychiatry. 2017 Nov;88(11):917-924. doi: 10.1136/jnnp-2017-315573. Epub 2017 Jul 14.
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Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial.依达拉奉在明确诊断的肌萎缩侧索硬化症患者中的安全性和有效性:一项随机、双盲、安慰剂对照试验。
Lancet Neurol. 2017 Jul;16(7):505-512. doi: 10.1016/S1474-4422(17)30115-1. Epub 2017 May 15.
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Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.肌萎缩侧索硬化症与精神分裂症的遗传相关性。
Nat Commun. 2017 Mar 21;8:14774. doi: 10.1038/ncomms14774.
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Lancet Neurol. 2017 Mar;16(3):208-216. doi: 10.1016/S1474-4422(16)30399-4. Epub 2017 Jan 28.
8
The standard of care in amyotrophic lateral sclerosis: a centralised multidisciplinary clinic encounter sets a new benchmark for a uniquely challenging neurodegenerative disorder.肌萎缩侧索硬化症的护理标准:集中式多学科门诊会诊为这一极具挑战性的神经退行性疾病树立了新的标杆。
J Neurol Neurosurg Psychiatry. 2015 May;86(5):481-2. doi: 10.1136/jnnp-2014-309829. Epub 2014 Dec 30.
9
Amyotrophic lateral sclerosis.肌萎缩性侧索硬化症。
Lancet. 2011 Mar 12;377(9769):942-55. doi: 10.1016/S0140-6736(10)61156-7. Epub 2011 Feb 4.