与谷氨酸脱羧酶抗体相关的自身免疫性脑炎：病例系列
Autoimmune encephalitis associated with glutamic acid decarboxylase antibodies: a case series.
作者信息
Incecik Faruk, Herguner Ozlem M, Besen Seyda, Yılmaz Mustafa
机构信息
Department of Pediatric Neurology, Cukurova University Faculty of Medicine, Adana, Turkey.
Department of Pediatric Immunology, Cukurova University Faculty of Medicine, Adana, Turkey.
出版信息
Acta Neurol Belg. 2018 Sep;118(3):411-414. doi: 10.1007/s13760-018-0880-5. Epub 2018 Jan 18.
Antibodies against glutamic acid decarboxylase (GAD) are associated with various neurologic conditions described in patients including stiff person syndrome, cerebellar ataxia, refractory epilepsy, limbic and extralimbic encephalitis. GAD antibodies-related limbic encephalitis cases are well described; reports of extralimbic involvement are limited. We describe four cases of GAD antibody-related autoimmune encephalitis. Three of them had extralimbic involvement and only one had limbic encephalitis.
抗谷氨酸脱羧酶（GAD）抗体与患者所描述的多种神经系统疾病相关，包括僵人综合征、小脑共济失调、难治性癫痫、边缘叶和边缘叶以外的脑炎。GAD抗体相关的边缘叶脑炎病例已有充分描述；边缘叶以外受累的报道有限。我们描述了4例GAD抗体相关的自身免疫性脑炎病例。其中3例有边缘叶以外受累，仅1例有边缘叶脑炎。
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