Kearney Hugh, Cryan Jane B, Looby Seamus, Brett Francesca M, Farrell Michael A, Buckley Patrick G
Clin Neuropathol. 2018 Mar/Apr;37(2):68-73. doi: 10.5414/NP301089.
Intracranial collision tumors are composed of two histologically distinct but merging components, and are rare. Their genetic profile has rarely been described. Comparative genome hybridization of a combined meningioma and oligodendroglioma demonstrated deletion of chromosome 22q and of 19q in both tumors. Somatic deletion of chromosome 22q and 19q is associated with development of an intracranial collision tumor. .
颅内碰撞瘤由两个组织学上不同但相互融合的成分组成，较为罕见。其基因特征鲜有描述。一例合并脑膜瘤和少突胶质细胞瘤的比较基因组杂交显示，两种肿瘤均存在22号染色体q臂和19号染色体q臂缺失。22号染色体q臂和19号染色体q臂的体细胞缺失与颅内碰撞瘤的发生有关。
