Rudolph Abby, Tobin Karin, Rudolph Jonathan, Latkin Carl
Department of Epidemiology, Boston University School of Public Health, Boston, MA, United States.
Department of Health, Behavior, and Society, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States.
JMIR Public Health Surveill. 2018 Jan 19;4(1):e12. doi: 10.2196/publichealth.8581.
Although studies that characterize the risk environment by linking contextual factors with individual-level data have advanced infectious disease and substance use research, there are opportunities to refine how we define relevant neighborhood exposures; this can in turn reduce the potential for exposure misclassification. For example, for those who do not inject at home, injection risk behaviors may be more influenced by the environment where they inject than where they live. Similarly, among those who spend more time away from home, a measure that accounts for different neighborhood exposures by weighting each unique location proportional to the percentage of time spent there may be more correlated with health behaviors than one's residential environment.
This study aimed to develop a Web-based application that interacts with Google Maps application program interfaces (APIs) to collect contextually relevant locations and the amount of time spent in each. Our analysis examined the extent of overlap across different location types and compared different approaches for classifying neighborhood exposure.
Between May 2014 and March 2017, 547 participants enrolled in a Baltimore HIV care and prevention study completed an interviewer-administered Web-based survey that collected information about where participants were recruited, worked, lived, socialized, injected drugs, and spent most of their time. For each location, participants gave an address or intersection which they confirmed using Google Map and Street views. Geographic coordinates (and hours spent in each location) were joined to neighborhood indicators by Community Statistical Area (CSA). We computed a weighted exposure based on the proportion of time spent in each unique location. We compared neighborhood exposures based on each of the different location types with one another and the weighted exposure using analysis of variance with Bonferroni corrections to account for multiple comparisons.
Participants reported spending the most time at home, followed by the location where they injected drugs. Injection locations overlapped most frequently with locations where people reported socializing and living or sleeping. The least time was spent in the locations where participants reported earning money and being recruited for the study; these locations were also the least likely to overlap with other location types. We observed statistically significant differences in neighborhood exposures according to the approach used. Overall, people reported earning money in higher-income neighborhoods and being recruited for the study and injecting in neighborhoods with more violent crime, abandoned houses, and poverty.
This analysis revealed statistically significant differences in neighborhood exposures when defined by different locations or weighted based on exposure time. Future analyses are needed to determine which exposure measures are most strongly associated with health and risk behaviors and to explore whether associations between individual-level behaviors and neighborhood exposures are modified by exposure times.
尽管通过将环境因素与个体层面数据相联系来描述风险环境的研究推动了传染病和物质使用研究的发展,但仍有机会改进我们对相关社区暴露的定义;这反过来可以降低暴露错误分类的可能性。例如,对于不在家注射的人来说,注射风险行为可能更多地受到他们注射地点的环境影响,而不是居住地点的影响。同样,对于那些离家时间较长的人来说,一种通过根据在每个独特地点花费的时间百分比对其进行加权来考虑不同社区暴露的测量方法,可能比居住环境与健康行为的相关性更强。
本研究旨在开发一个基于网络的应用程序,该程序与谷歌地图应用程序编程接口(API)交互,以收集与环境相关的地点以及在每个地点花费的时间。我们的分析考察了不同地点类型之间的重叠程度,并比较了对社区暴露进行分类的不同方法。
在2014年5月至2017年3月期间,参与巴尔的摩艾滋病毒护理与预防研究的547名参与者完成了一项由访谈员实施的基于网络的调查,该调查收集了参与者被招募、工作、居住、社交、注射毒品以及大部分时间所在地点的信息。对于每个地点,参与者提供一个地址或十字路口,并使用谷歌地图和街景进行确认。地理坐标(以及在每个地点花费的时间)通过社区统计区域(CSA)与社区指标相关联。我们根据在每个独特地点花费的时间比例计算加权暴露。我们使用方差分析和邦费罗尼校正来考虑多重比较,比较了基于不同地点类型的社区暴露以及加权暴露。
参与者报告在家中花费的时间最多,其次是注射毒品的地点。注射地点与人们报告社交、居住或睡觉的地点重叠最为频繁。在参与者报告赚钱和参与研究招募的地点花费的时间最少;这些地点也最不可能与其他地点类型重叠。根据所使用的方法,我们观察到社区暴露存在统计学上的显著差异。总体而言,人们报告在高收入社区赚钱,在暴力犯罪、废弃房屋和贫困较多的社区参与研究招募和注射毒品。
该分析揭示了根据不同地点定义或基于暴露时间加权时,社区暴露存在统计学上的显著差异。未来需要进行分析,以确定哪些暴露测量与健康和风险行为关联最紧密,并探讨个体层面行为与社区暴露之间的关联是否会因暴露时间而改变。