Dorros G, Janke L M
Cardiol Clin. 1985 Feb;3(1):49-71.
Coronary artery bypass surgery not only provides symptomatic relief but also may prolong life in a significant percentage of patients. Repeat bypass surgery succeeds in providing symptomatic relief in a lesser number of patients, but it is associated with a higher morbidity and mortality than primary operations. Angioplasty, an interventional, therapeutic catheter technique, is applicable to a large number of patients who have undergone bypass surgery and who are sufficiently symptomatic to require consideration of another revascularization procedure. The gratifying results of successful lesion dilatation coupled with clinical improvement of the patient, the acceptable mortality and morbidity statistics, and the long-term symptomatic relief are comparable to those for repeat coronary bypass graft surgery. In addition, technologic advances in angioplasty equipment, as well as more knowledgeable interventionists, will enable more lesions to be successfully reached, traversed, and dilated with, it is hoped, a lower morbidity and mortality. We would estimate that 30 to 50 per cent of those patients requiring repeat revascularization operations today can undergo an angioplasty procedure with at least comparable clinical results and better morbidity and mortality statistics than those achieved with repeat bypass surgery. Selected patients underwent transluminal coronary angioplasty of varying combinations of arterial and/or vein graft stenoses. A multiple dilatation procedure was defined as successful when dilatation was achieved in all lesions in which it was attempted or when the considered-critical stenosis was dilated successfully and the patient was clinically improved. Angioplasty was successful in 93 per cent of all lesions in which it was attempted, and these successful dilatations produced a clinical improvement in 92 per cent of the patients. No complication whatsoever was experienced in 81 per cent of cases. The complications encountered included a 1.3 per cent mortality rate, a myocardial infarction rate of 6.9 per cent (3.0 per cent per lesion attempted), and an emergency surgery rate of 2.6 per cent (1.1 per cent per lesion attempted). Follow-up data show that a sustained clinical improvement was obtained in 96.8 per cent of the patients in whom the procedure was successful (with or without a repeat angioplasty). These data indicate that multiple coronary angioplasties can be performed during the same procedure, that clinical improvement can be achieved, and that the complication rate is acceptable.(ABSTRACT TRUNCATED AT 400 WORDS)
冠状动脉搭桥手术不仅能缓解症状,而且在相当比例的患者中还可能延长生命。再次搭桥手术能使较少数量的患者症状得到缓解,但与初次手术相比,其发病率和死亡率更高。血管成形术是一种介入性治疗导管技术,适用于大量接受过搭桥手术且症状严重、需要考虑再次血运重建手术的患者。成功扩张病变并使患者临床症状改善所带来的令人满意的结果、可接受的死亡率和发病率统计数据,以及长期的症状缓解,与再次冠状动脉搭桥移植手术相当。此外,血管成形术设备的技术进步以及更有经验的介入专家,将使更多病变能够成功到达、穿过并扩张,有望降低发病率和死亡率。我们估计,如今需要再次血运重建手术的患者中,有30%至50%可以接受血管成形术,其临床效果至少与再次搭桥手术相当,且发病率和死亡率统计数据更好。部分患者接受了对动脉和/或静脉移植血管狭窄进行不同组合的经皮冠状动脉血管成形术。当在所尝试的所有病变中都实现了扩张,或者当被视为关键的狭窄成功扩张且患者临床症状改善时,多部位扩张手术被定义为成功。在所尝试的所有病变中,血管成形术的成功率为93%,这些成功的扩张使92%的患者临床症状得到改善。81%的病例未出现任何并发症。所遇到的并发症包括1.3%的死亡率、6.9%的心肌梗死率(每尝试扩张一个病变的发生率为3.0%)以及2.6%的急诊手术率(每尝试扩张一个病变的发生率为1.1%)。随访数据显示,手术成功的患者(无论是否再次进行血管成形术)中有96.8%获得了持续的临床改善。这些数据表明,在同一手术过程中可以进行多次冠状动脉血管成形术,能够实现临床改善,且并发症发生率是可接受的。(摘要截选至400字)