School of Chemical and Materials Engineering, National University of Sciences and Technology, Islamabad, Pakistan.
School of Chemical and Materials Engineering, National University of Sciences and Technology, Islamabad, Pakistan.
Carbohydr Polym. 2018 Mar 15;184:453-464. doi: 10.1016/j.carbpol.2017.12.068. Epub 2018 Jan 3.
Antimicrobial packaging is an area of emerging interest and is rapidly expanding with application of nanotechnology. The present work investigates the effect of nanocellulose (NC) and Ag NPs on the physical, mechanical and thermal properties of PVA nanocomposite films. The tensile strength of PVA was improved from 5.52 ± 0.27 MPa to 12.32 ± 0.61 MPa when filled with 8 wt% of NC. Nanocomposite films exhibited strong antibacterial activity against both Staphylococcus aureus (MRSA) and Escherichia coli (DH5-alpha). The maximum inhibition zone at 0.5 g Ag NPs with 12 wt% NC against DH5-alpha was 14 ± 0.70 mm. While, the maximum inhibition zone at 0.3 g Ag NPs for 16 wt% NC was 13.6 ± 0.68 mm against MRSA. Moreover, nanocomposites films have no cytotoxicity effect on HepG2 and cell viability was more than 90%. Based on mechanical properties and antibacterial potential of the developed nanocomposite films, it can be envisaged to use these films for packaging applications.
抗菌包装是一个新兴的研究领域,随着纳米技术的应用,其发展迅速。本研究考察了纳米纤维素(NC)和 Ag NPs 对 PVA 纳米复合材料薄膜物理、机械和热性能的影响。当填充 8wt%的 NC 时,PVA 的拉伸强度从 5.52±0.27 MPa 提高到 12.32±0.61 MPa。纳米复合材料薄膜对金黄色葡萄球菌(MRSA)和大肠杆菌(DH5-alpha)均表现出较强的抗菌活性。在 0.5 g Ag NPs 和 12wt%NC 下,对 DH5-alpha 的最大抑菌圈为 14±0.70mm。而在 0.3 g Ag NPs 和 16wt%NC 下,对 MRSA 的最大抑菌圈为 13.6±0.68mm。此外,纳米复合材料薄膜对 HepG2 无细胞毒性作用,细胞存活率超过 90%。基于所开发的纳米复合材料薄膜的机械性能和抗菌潜力,可以设想将这些薄膜用于包装应用。