Pyo Hannah, Kim Bo Ra, Park Mina, Hong Jeong Hee, Kim Eun Joo
Department of Physical Medicine and Rehabilitation, National Rehabilitation Center, Seoul, Korea.
Department of Urology, Dankook University College of Medicine, Cheonan, Korea.
Ann Rehabil Med. 2017 Dec;41(6):935-943. doi: 10.5535/arm.2017.41.6.935. Epub 2017 Dec 28.
To identify the effects of overactive bladder (OAB) symptoms on the health-related quality of life (HRQOL) in stroke patients since OAB symptoms are common in such patients, but their effects on stroke rehabilitation over time are unclear.
This study included 30 post-acute stroke patients who had been admitted for rehabilitation treatments. All participants completed a questionnaire evaluating urinary symptoms, including the Overactive Bladder Symptom Score (OABSS) and general HRQOL with a Short-Form 36 (SF-36) health survey. We assessed their performance in terms of the Function Ambulation Category, Modified Rankin Scale (MRS), Modified Barthel Index, and Mini-Mental State Examination (MMSE). All assessments were carried out twice at baseline and at 3 months. We divided patients into an OAB and non-OAB group with OABSS. A correlation analysis and multivariate regression were then performed.
All performance scales showed an improvement over 3 months in the non-OAB group (n=18; p<0.02), but, MRS and MMSE scores did not improve significantly in the OAB group (n=12) (p=0.15 and p=0.20, respectively). In the OAB group, the vitality and mental health scores significantly decreased over 3 months (p=0.011 and p=0,041, respectively), and the mental component summary (MCS) score showed a marginal decrease over 3 months (p=0.05). A multivariate regression analysis revealed that OAB symptoms were negatively correlated with the 3 months MCS score (B=-8.15, p=0.034).
These results indicated that OAB symptoms could have negative effects on HRQOL and performance in patients suffering from a stroke.
鉴于膀胱过度活动症(OAB)症状在中风患者中很常见,但随着时间推移其对中风康复的影响尚不清楚,本研究旨在确定OAB症状对中风患者健康相关生活质量(HRQOL)的影响。
本研究纳入了30例因康复治疗入院的急性中风后患者。所有参与者均完成了一份评估泌尿症状的问卷,包括膀胱过度活动症症状评分(OABSS),并通过简短36项健康调查(SF-36)评估一般HRQOL。我们根据功能步行分类、改良Rankin量表(MRS)、改良Barthel指数和简易精神状态检查(MMSE)评估他们的表现。所有评估在基线和3个月时各进行一次。我们根据OABSS将患者分为OAB组和非OAB组。然后进行相关分析和多变量回归分析。
非OAB组(n = 18)在3个月内所有表现量表均有改善(p < 0.02),但OAB组(n = 12)的MRS和MMSE评分未显著改善(分别为p = 0.15和p = 0.20)。在OAB组中,活力和心理健康评分在3个月内显著下降(分别为p = 0.011和p = 0.041),精神成分总结(MCS)评分在3个月内略有下降(p = 0.05)。多变量回归分析显示,OAB症状与3个月时的MCS评分呈负相关(B = -8.15,p = 0.034)。
这些结果表明,OAB症状可能对中风患者的HRQOL和表现产生负面影响。