Wollenek G, Laufer G, Haschkovitz H, Wolner E
Herz. 1985 Dec;10(6):351-6.
Experimental studies have confirmed the feasibility of removing thrombotic material and atheromatous plaques with laser energy. Secondary to the heat generated at the site of conventional, continuous-wave laser radiation, thermic lesions of the vascular wall can be observed as adverse reactions. In the clinical setting, these lesions could prove to be of substantial potential danger. The energy emitted from the excimer laser, in the lower UV range, does not result in thermic damage. The luminal widening rendered is well delineated and the newly-created surfaces are relatively smooth. The extent of ablation is highly predictable. Problems dealing with transmissions of the UV laser energy remain to be solved. Nevertheless, high-energy, pulsed NdYAG- or argon laser systems, at least for medium-term periods, would appear to represent a useful alternative.
实验研究已证实利用激光能量去除血栓物质和动脉粥样斑块的可行性。在传统连续波激光辐射部位产生的热量会引发血管壁的热损伤，这是一种不良反应。在临床环境中，这些损伤可能具有极大的潜在危险。准分子激光发出的处于较低紫外线范围的能量不会导致热损伤。所产生的管腔扩张界限清晰，新形成的表面相对光滑。消融范围具有高度可预测性。处理紫外线激光能量传输的问题仍有待解决。然而，高能脉冲钕钇铝石榴石激光或氩激光系统，至少在中期内，似乎是一种有用的替代方法。
