CAS Key Laboratory of Soft Matter Chemistry, Hefei National Laboratory for Physical Sciences at Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China.
Org Biomol Chem. 2018 Feb 7;16(6):1029-1036. doi: 10.1039/c7ob02947k.
The nickel-catalyzed cross-coupling reaction of β-carbonyl alkenyl pivalates with arylzinc reagents generates 3-aryl-substituted α,β-unsaturated carbonyl compounds via C-O bond cleavage. The reaction features mild reaction conditions, a wide scope of substrates, and good functional group tolerance.
镍催化的β-羰基烯基特戊酸酯与芳基锌试剂的交叉偶联反应通过 C-O 键断裂生成 3-芳基取代的α,β-不饱和羰基化合物。该反应具有反应条件温和、底物范围广、官能团容忍性好等特点。
