Clin Nucl Med. 2018 Mar;43(3):e98-e100. doi: 10.1097/RLU.0000000000001971.
A 38-year-old woman was referred for staging of an alveolar rhabdomyosarcoma revealed by a breast metastasis with unknown primary. Whole-body F-FDG PET/CT localized the primary tumor as an asymptomatic soft tissue lesion of the right foot with a significant uptake. PET/CT detected hepatic and pancreatic metastases and also showed a multifocal bone marrow involvement, which was not detected by the contrast-enhanced CT. These results led to a significant change in treatment management as the patient received local radiotherapy of the primitive lesion and polychemotherapy.
一位 38 岁女性因乳腺转移伴未知原发性疾病的肺泡横纹肌肉瘤而被转介进行分期检查。全身 F-FDG PET/CT 将原发性肿瘤定位为右脚无症状软组织病变,摄取明显。PET/CT 检测到肝和胰腺转移,还显示多灶性骨髓受累,而增强 CT 未检测到。这些结果导致治疗管理发生重大变化,因为患者接受了原始病变的局部放疗和多化疗。