From the Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Clin Nucl Med. 2018 Mar;43(3):195-198. doi: 10.1097/RLU.0000000000001979.
We present a case of posterior reversible encephalopathy syndrome (PRES) in a pediatric patient with Burkitt's lymphoma predominantly involving the bone marrow. F-FDG PET/CT scan obtained after the first cycle of chemotherapy, complicated by acute kidney injury, hypertension, tumor lysis syndrome, and lethargy with focal neurological symptoms, showed a favorable marrow and lymph node response but increased FDG uptake in the bilateral frontal and occipital cortical/subcortical regions. Brain MRI was consistent with PRES. The patient was managed with IV hydration and blood pressure control with symptom resolution. This case shows the F-FDG uptake pattern of PRES in postchemotherapy setting.
我们报告了一例儿童伯基特淋巴瘤患者,主要累及骨髓的后部可逆性脑病综合征(PRES)。该患者在第一周期化疗后发生急性肾损伤、高血压、肿瘤溶解综合征和嗜睡伴局灶性神经症状,行 F-FDG PET/CT 扫描后显示骨髓和淋巴结反应良好,但双侧额极和枕叶皮质/皮质下区域 FDG 摄取增加。脑部 MRI 与 PRES 一致。患者通过静脉补液和血压控制进行治疗,症状得到缓解。该病例显示了化疗后 PRES 的 F-FDG 摄取模式。