Cesbron J Y, Maillet F, Valance J, Langlet N, Kazatchkine M
Presse Med. 1985 Dec 21;14(45):2287-9.
The complement system functions to protect the individual against infectious agents. Deficiencies of the late-acting complement proteins C5-C8 are associated with an increased susceptibility to Neisseria infection. This paper describes a deficiency in C5 in a Caucasoid family from the north of France that was revealed by the occurrence of a N. meningitidis meningitis in the homozygous C5-deficient propositus.
补体系统的功能是保护个体抵御感染因子。晚期补体蛋白C5 - C8的缺陷与感染奈瑟菌的易感性增加有关。本文描述了来自法国北部一个白种人家庭中的C5缺陷情况，该缺陷是由纯合C5缺陷的先证者发生脑膜炎奈瑟菌脑膜炎而发现的。
