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诺瓦敏与磷酸三钙对人工龋再矿化作用的比较评价:一项体外研究

Comparative Evaluation of Remineralizing Effect of Novamin and Tricalcium Phosphate on Artificial Caries: An in vitro Study.

作者信息

Jagga Umang, Paul Uttam, Padmanabhan Vivek, Kashyap Arpita, Guram Guneet, Keswani Kiran

机构信息

Department of Pediatric and Preventive Dentistry, Sri Sukhmani Dental College & Hospital, Dera Bassi, Punjab, India.

Private Practitioner, Department of Conservative Dentistry and Endodontics, Precision Dental Clinic & Implant Centre, Guwahati Assam, India, e-mail:

出版信息

J Contemp Dent Pract. 2018 Jan 1;19(1):109-112. doi: 10.5005/jp-journals-10024-2221.

Abstract

AIM

The aim of the present study was to compare the remineralizing efficacy of novamin and tricalcium phosphate (TCP).

MATERIALS AND METHODS

Nail varnish was coated to a total of 30 sound human premolars except for 5 mm × 5 mm window. Baseline microhardness was measured for all test samples. Artificial carious lesions were created for all teeth by subjecting them to demineralization process. Then microhardness of demineralized lesion was measured. Later artificial caries teeth were equally divided into two groups to treat with remineralization solution for 10 days; group I: novamin and group II: TCP. After 10 days of pH cycling, microhardness was measured. The data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) statistical software from Chicago SPSS Inc., version 21 and using analysis of variance (ANOVA) post hoc multiple comparisons test for intergroup and significant difference at p < 0.05.

RESULTS

In the present study, group I indicated a higher value for remineralization compared with group II (p < 0.05).

CONCLUSION

The present study showed that both novamin and TCP were effective in remineralizing the carious lesions.

CLINICAL SIGNIFICANCE

This study evaluates the remineralizing potential of novamin and TCP on initial carious lesions.

摘要

目的

本研究旨在比较诺瓦敏(Novamin)和磷酸三钙(TCP)的再矿化效果。

材料与方法

除5mm×5mm的窗口外,在总共30颗完好的人类前磨牙上涂指甲油。测量所有测试样本的基线显微硬度。通过脱矿过程对所有牙齿造成人工龋损。然后测量脱矿病变的显微硬度。之后将人工龋损牙齿平均分为两组,用再矿化溶液处理10天;第一组:诺瓦敏,第二组:磷酸三钙。经过10天的pH循环后,测量显微硬度。使用芝加哥SPSS公司的社会科学统计软件包(SPSS)统计软件版本21对数据进行统计分析,并使用方差分析(ANOVA)事后多重比较检验组间差异,p < 0.05为有显著差异。

结果

在本研究中,第一组的再矿化值高于第二组(p < 0.05)。

结论

本研究表明,诺瓦敏和磷酸三钙在使龋损再矿化方面均有效。

临床意义

本研究评估了诺瓦敏和磷酸三钙对初始龋损的再矿化潜力。

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