Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine and Institute of Neurosciences, Newcastle University, Newcastle upon Tyne, UK.
Nat Rev Mol Cell Biol. 2018 Jan 23;19(2):71-72. doi: 10.1038/nrm.2018.3.
Mitochondrial DNA is maternally inherited, and pathogenic mutations cause a range of life-limiting conditions. Recent studies indicate that transmission of pathogenic mutations may be prevented by reproductive technologies designed to replace the mitochondria in eggs from affected women.
线粒体 DNA 通过母系遗传，如果致病性突变会导致一系列危及生命的疾病。最近的研究表明，通过设计的生殖技术，可以替换携带致病性突变的女性卵子中的线粒体，从而防止致病性突变的传递。
