年轻女性中的抗N-甲基-D-天冬氨酸受体脑炎
Anti-N-Methyl-D-Aspartate-Receptor Encephalitis in Young Females.
作者信息
Kumari Kamlesh, Sahni Neeru, Kumari Vimla, Saini Vikas
机构信息
Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Department of Gynaecology and Obstetric, Dr. S.N. Medical College Jodhpur, Rajasthan, India.
出版信息
Turk J Anaesthesiol Reanim. 2017 Dec;45(6):377-379. doi: 10.5152/TJAR.2017.74508. Epub 2017 Sep 15.
Abstract
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune-mediated disease commonly associated with ovarian teratoma. Anti-NMDA-receptor autoantibodies disrupt NMDA function leading to the development of psychosis, seizures and autonomic dysfunction. The treatment includes underlying tumour resection and immunosuppression. Slow recovery and unpredictable clinical course makes intensive care management of these patients challenging. We report the management of two young female patients with anti-NMDA-receptor encephalitis associated with ovarian teratoma.
摘要
抗N-甲基-D-天冬氨酸（NMDA）受体脑炎是一种通常与卵巢畸胎瘤相关的免疫介导性疾病。抗NMDA受体自身抗体破坏NMDA功能，导致精神病、癫痫发作和自主神经功能障碍的发生。治疗包括切除潜在肿瘤和免疫抑制。恢复缓慢且临床病程不可预测，使得对这些患者的重症监护管理具有挑战性。我们报告了两名患有与卵巢畸胎瘤相关的抗NMDA受体脑炎的年轻女性患者的治疗情况。
相似文献
1
Anti-N-Methyl-D-Aspartate-Receptor Encephalitis in Young Females.年轻女性中的抗N-甲基-D-天冬氨酸受体脑炎
Turk J Anaesthesiol Reanim. 2017 Dec;45(6):377-379. doi: 10.5152/TJAR.2017.74508. Epub 2017 Sep 15.
2
Anti-N-methyl-D-aspartate receptor encephalitis with an imaging-invisible ovarian teratoma: a case report.伴有影像学隐匿性卵巢畸胎瘤的抗N-甲基-D-天冬氨酸受体脑炎：一例报告
J Med Case Rep. 2016 Oct 24;10(1):296. doi: 10.1186/s13256-016-1067-4.
3
Early operative treatment of anti-N-methyl D-aspartate (anti-NMDA) receptor encephalitis in a patient with ovarian teratoma.卵巢畸胎瘤患者抗N-甲基-D-天冬氨酸（anti-NMDA）受体脑炎的早期手术治疗
Clin Exp Obstet Gynecol. 2015;42(6):819-21.
4
Anti-N-methyl-D-aspartate receptor encephalitis associated with an ovarian teratoma: two cases report and anesthesia considerations.与卵巢畸胎瘤相关的抗N-甲基-D-天冬氨酸受体脑炎：两例报告及麻醉注意事项
BMC Anesthesiol. 2015 Oct 16;15:150. doi: 10.1186/s12871-015-0134-5.
5
Surgical outcomes in patients with anti-N-methyl D-aspartate receptor encephalitis with ovarian teratoma.抗 N-甲基-D-天冬氨酸受体脑炎合并卵巢畸胎瘤患者的手术结局。
Am J Obstet Gynecol. 2019 Nov;221(5):485.e1-485.e10. doi: 10.1016/j.ajog.2019.05.026. Epub 2019 May 22.
6
Non-tumor-Associated Anti-N-Methyl-D-Aspartate (NMDA) Receptor Encephalitis in Chinese Girls With Positive Anti-thyroid Antibodies.抗甲状腺抗体阳性中国女孩中的非肿瘤相关性抗N-甲基-D-天冬氨酸（NMDA）受体脑炎
J Child Neurol. 2015 Oct;30(12):1582-5. doi: 10.1177/0883073815575365. Epub 2015 Mar 19.
7
Histopathological characterization of the neuroglial tissue in ovarian teratoma associated with anti-N-methyl-D-aspartate (NMDA) receptor encephalitis.与抗N-甲基-D-天冬氨酸（NMDA）受体脑炎相关的卵巢畸胎瘤中神经胶质组织的组织病理学特征
Pathol Int. 2018 Dec;68(12):677-684. doi: 10.1111/pin.12732. Epub 2018 Nov 14.
8
Anti-N-Methyl-D-Aspartate Encephalitis as Paraneoplastic Manifestation of Germ-Cells Tumours: A Cases Report and Literature Review.抗N-甲基-D-天冬氨酸受体脑炎作为生殖细胞肿瘤的副肿瘤表现：一例报告及文献综述
Case Reports Immunol. 2019 Mar 10;2019:4762937. doi: 10.1155/2019/4762937. eCollection 2019.
9
[Anti-nMDA receptor encephalitis--clinical manifestations and pathophysiology].[抗N-甲基-D-天冬氨酸受体脑炎——临床表现与病理生理学]
Brain Nerve. 2008 Sep;60(9):1047-60.
10
Anti-N-methyl-D-aspartate Receptor Encephalitis.抗N-甲基-D-天冬氨酸受体脑炎
Cureus. 2019 Jul 22;11(7):e5192. doi: 10.7759/cureus.5192.
引用本文的文献
1
Anti--methyl D-aspartate Receptor Encephalitis in India: A Literature Review.印度的抗N-甲基-D-天冬氨酸受体脑炎：文献综述
Ann Indian Acad Neurol. 2023 Jan-Feb;26(1):17-32. doi: 10.4103/aian.aian_519_22. Epub 2023 Jan 25.
本文引用的文献
1
Anti-NMDA encephalitis: an uncommon, autoimmune mediated form of encephalitis.抗N-甲基-D-天冬氨酸受体（NMDA）脑炎：一种罕见的、自身免疫介导的脑炎形式。
J Radiol Case Rep. 2014 Aug 31;8(8):1-6. doi: 10.3941/jrcr.v8i8.1566. eCollection 2014 Aug.
2
Anesthetic management of ovarian teratoma excision associated with anti-N-methyl-D-aspartate receptor encephalitis.与抗N-甲基-D-天冬氨酸受体脑炎相关的卵巢畸胎瘤切除术的麻醉管理
Int J Gynaecol Obstet. 2011 Dec;115(3):291-2. doi: 10.1016/j.ijgo.2011.07.028. Epub 2011 Sep 25.
3
Case report: Anti-N-methyl-D-aspartate receptor encephalitis and its anesthetic implications.病例报告：抗 N-甲基-D-天冬氨酸受体脑炎及其麻醉相关问题。
Anesth Analg. 2011 Nov;113(5):1188-91. doi: 10.1213/ANE.0b013e31822b8a7d. Epub 2011 Sep 14.
4
Autoantibodies associated with diseases of the CNS: new developments and future challenges.与中枢神经系统疾病相关的自身抗体：新进展和未来挑战。
Lancet Neurol. 2011 Aug;10(8):759-72. doi: 10.1016/S1474-4422(11)70096-5.
5
Anaesthesia for a patient with paraneoplastic limbic encephalitis with ovarian teratoma: relationship to anti-N-methyl-D-aspartate receptor antibodies.卵巢畸胎瘤伴副肿瘤性边缘叶脑炎患者的麻醉：与抗 N-甲基-D-天冬氨酸受体抗体的关系。
Anaesthesia. 2011 Jun;66(6):515-8. doi: 10.1111/j.1365-2044.2011.06707.x. Epub 2011 Apr 4.
6
NMDA receptor antibody encephalitis.N-甲基-D-天冬氨酸受体抗体脑炎。
Curr Neurol Neurosci Rep. 2011 Jun;11(3):298-304. doi: 10.1007/s11910-011-0186-y.
7
Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis.抗 NMDAR 脑炎患者的临床经验和实验室研究。
Lancet Neurol. 2011 Jan;10(1):63-74. doi: 10.1016/S1474-4422(10)70253-2.
8
Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis.抗 NMDA 受体脑炎的细胞和突触机制。
J Neurosci. 2010 Apr 28;30(17):5866-75. doi: 10.1523/JNEUROSCI.0167-10.2010.
9
Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies.抗N-甲基-D-天冬氨酸受体脑炎：病例系列及抗体作用分析
Lancet Neurol. 2008 Dec;7(12):1091-8. doi: 10.1016/S1474-4422(08)70224-2. Epub 2008 Oct 11.
10
Psychosis associated with anti-N-methyl-D-aspartate receptor antibodies.与抗N-甲基-D-天冬氨酸受体抗体相关的精神病
CNS Spectr. 2008 Aug;13(8):699-703. doi: 10.1017/s109285290001378x.
Zotero 插件