剖宫产术后家庭使用阿片类药物：产科医生应开多少片阿片类药物？
Home opioid use following cesarean delivery: How many opioid tablets should obstetricians prescribe?
作者信息
Schmidt Payton, Berger Mitchell B, Day Lori, Swenson Carolyn W
机构信息
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA.
出版信息
J Obstet Gynaecol Res. 2018 Apr;44(4):723-729. doi: 10.1111/jog.13579. Epub 2018 Jan 23.
Abstract
AIM
To quantify home opioid use after cesarean delivery and identify factors associated with increased opioid use.
METHODS
A convenience sample of women discharged by postoperative day 2 following a term cesarean delivery of a singleton fetus from May 2015 to May 2016 were contacted 2 weeks post-partum and questioned regarding opioid use, pain control and pain expectations.
RESULTS
Among 141 women included in the analysis, the median number of opioid tablets used was 36 (interquartile range 16-45) and the median number prescribed was 60 (interquartile range 42-65). Logistic regression identified operative time ≥59.5 min and number of opioid tablets prescribed as two factors independently associated with opioid use in the top quartile.
CONCLUSION
In the first 2 weeks post-partum, 75% of women used 45 or fewer opioid tablets. Operative time over 1 h and increased number of opioid tablets prescribed are factors associated with higher post-partum opioid use.
摘要
目的
量化剖宫产术后家庭阿片类药物的使用情况，并确定与阿片类药物使用增加相关的因素。
方法
对2015年5月至2016年5月因单胎足月剖宫产术后第2天出院的女性进行便利抽样，在产后2周联系她们，询问阿片类药物使用、疼痛控制和疼痛预期情况。
结果
纳入分析的141名女性中，使用阿片类药物片剂的中位数为36片（四分位间距16 - 45片），处方的中位数为60片（四分位间距42 - 65片）。逻辑回归分析确定手术时间≥59.5分钟和阿片类药物片剂处方数量是与处于四分位最高值的阿片类药物使用独立相关的两个因素。
结论
在产后的前2周，75%的女性使用了45片或更少的阿片类药物片剂。手术时间超过1小时和阿片类药物片剂处方数量增加是与产后阿片类药物使用量较高相关的因素。
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