Kupriyanova T A, Koren E V, Alabusheva N N
Moscow Research Institute of Psychiatry - the branch of FSBSI 'Serbsky Federal Medical Research Center of Psychiatry and Narcology', Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(11. Vyp. 2):75-79. doi: 10.17116/jnevro201711711275-79.
To assess short-term efficiency of hopantenic acid (pantogam) in the treatment of children with hyperkinetic behavior disorder, in whom the previous treatment with atomoxetine was not efficient.
Twenty-four children (16 boys and 8 girls), aged 6-11 years, diagnosed with hyperkinetic behavior disorder (ICD-10 item F90.1) were enrolled in this open non-randomized study.
A short-term positive therapeutic dynamics was observed when introducing hopantenic acid (pantogam) augmentation strategy to existing atomoxetine therapy. Qualitative improvements in children's state were found not only in the ability to control symptoms but also in their social functioning levels and quality of life. The proposed therapeutic strategy can help to improve treatment outcomes for children with certain clinical forms of hyperkinetic behavior disorder.
评估泛酸(潘托伽)治疗患有多动行为障碍且先前使用托莫西汀治疗无效的儿童的短期疗效。
本开放性非随机研究纳入了24名年龄在6至11岁、被诊断为多动行为障碍(ICD - 10编码F90.1)的儿童(16名男孩和8名女孩)。
在现有托莫西汀治疗中引入泛酸(潘托伽)强化策略时,观察到了短期积极的治疗动态。不仅在控制症状的能力方面,而且在社交功能水平和生活质量方面都发现了儿童状态的质性改善。所提出的治疗策略有助于改善某些临床形式的多动行为障碍儿童的治疗效果。