Kozhieva M Kh, Melnikov M V, Rogovsky V S, Oleskin A V, Kabilov M R, Boyko A N
Pirogov Russian National Research Medical University, Moscow, Russia.
Pirogov Russian National Research Medical University, Moscow, Russia; Institute of Immunology, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(10. Vyp. 2):11-19. doi: 10.17116/jnevro201711710211-19.
Recently the relationship between gut microbiota changes and the development of immune-mediated diseases of the central nervous system (CNS) has been reported. This review presents literature data on the effect of gut microbiota on the function of the immune and nervous systems. The authors discuss possible mechanisms of the relationship between gut microbiota changes and CNS diseases on the model of multiple sclerosis (MS).
最近有报道称肠道微生物群的变化与中枢神经系统(CNS)免疫介导疾病的发展之间存在关联。这篇综述展示了关于肠道微生物群对免疫和神经系统功能影响的文献数据。作者们以多发性硬化症(MS)为模型,探讨了肠道微生物群变化与CNS疾病之间关系的可能机制。