Bakulin I S, Simaniv T O, Konovalov R N, Zakharova M N
Research Center of Neurology, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(10. Vyp. 2):20-23. doi: 10.17116/jnevro201711710220-23.
Neuromyelitis optica (Devic's disease) is a chronic autoimmune disease associated with the production of anti-bodies to aquaporin-4 (AQP4). Area postrema lesions is the third, after optic neuritis and myelitis, syndrome of opticomyelitis-related disorders. Clinical symptoms of this disorder include intractable nausea, vomiting and hiccups. In many cases, area postrema syndrome manifests as the first clinical symptom of a neuromyelitis optica spectrum disorder that hampers the diagnosis. The authors present a case report of a female patient with area postrema lesions developed several months before the first disabling attack of myelitis.
视神经脊髓炎（德维克病）是一种慢性自身免疫性疾病，与抗水通道蛋白4（AQP4）抗体的产生有关。最后区病变是视神经脊髓炎相关疾病综合征中，继视神经炎和脊髓炎之后的第三种综合征。这种疾病的临床症状包括顽固性恶心、呕吐和打嗝。在许多情况下，最后区综合征表现为视神经脊髓炎谱系障碍的首个临床症状，这会妨碍诊断。作者报告了一例女性患者的病例，该患者在首次致残性脊髓炎发作前几个月出现了最后区病变。
