Department of Oral Implantology, Affiliated Stomatological Hospital of Fujian Medical University, Fuzhou, China.
The State Key Laboratory Breeding Base of Basic Science of Stomatology & Key Laboratory of Oral Biomedicine Ministry of Education, Wuhan University, Wuhan, China.
Sci Rep. 2018 Jan 23;8(1):1451. doi: 10.1038/s41598-018-19515-7.
We performed a meta-analysis aimed to assess the clinical results after transalveolar sinus floor lift without bone grafting in the atrophic maxilla. A systematic electronic literature search was conducted in PubMed, Embase and The Cochrane Library, followed by a manual search. Two reviewers independently extracted study data and conducted quality assessments. Ten non-controlled studies including 1484 implants and eight controlled studies (5 RCTs and 3 prospective studies) including 817 implants (451 implants in the non-graft group) were enrolled in this study. The survival rate of implants via the graft-free method was 98% (95%CI 96% to 100%). There was no significant difference in the survival rate between the non-graft group and the graft group (RR: 1.02; p = 0.18). No statistically significant difference in marginal bone loss was detected between the groups at 12 months (0.57, p = 0.07) or 36 months (0.05, p = 0.61). The endo-sinus bone gain in the non-graft group was significantly lower than in the graft group at 12 months (-1.10, p = 0.0001) and 36 months (-0.74, p = 0.02). Hence, the available evidence suggests that predictable results could be acquired through transalveolar sinus floor lift without bone grafting, while there may be a trend toward more endo-sinus bone gain with bone grafts.
我们进行了一项荟萃分析,旨在评估在萎缩上颌无植骨的情况下经牙槽窦底提升的临床效果。在 PubMed、Embase 和 The Cochrane Library 中进行了系统的电子文献检索,然后进行了手动搜索。两位审查员独立提取研究数据并进行质量评估。本研究纳入了 10 项非对照研究(包括 1484 个种植体)和 8 项对照研究(5 项 RCT 和 3 项前瞻性研究)(非植骨组 451 个种植体)。无植骨方法的种植体存活率为 98%(95%CI 96%至 100%)。非植骨组和植骨组的种植体存活率无显著差异(RR:1.02;p=0.18)。两组在 12 个月(0.57,p=0.07)和 36 个月(0.05,p=0.61)时的边缘骨丧失无统计学差异。非植骨组在 12 个月(-1.10,p=0.0001)和 36 个月(-0.74,p=0.02)时的窦内骨增量明显低于植骨组。因此,现有证据表明,经牙槽窦底提升无植骨可获得可预测的效果,而植骨可能有更多窦内骨增量的趋势。