腹腔镜治疗胆囊穿孔的单中心经验

Single center experience in laparoscopic treatment of gallbladder perforation.

作者信息

Sahbaz Nuri Alper, Peker Kivanc Derya, Kabuli Hamit Ahmet, Gumusoglu Alpen Yahya, Alis Halil

机构信息

Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Department of General Surgery, Faculty of Medicine, Istanbul Aydın University, Istanbul, Turkey.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2017 Dec;12(4):372-377. doi: 10.5114/wiitm.2017.72321. Epub 2017 Dec 29.

Abstract

INTRODUCTION

Gallbladder perforation (GBP) is a rare disease with potential mortality. Previous series have reported an incidence of approximately 2-11% and it still continues to be a significant problem for surgeons.

AIM

To present our clinical experience with gallbladder perforation.

MATERIAL AND METHODS

The records of 2754 patients who received surgical treatment for cholelithiasis between 2010 and 2016 were reviewed retrospectively. One hundred thirty-three patients had gallbladder perforation. Age, gender, time from the onset of symptoms, diagnostic procedures, surgical treatment, morbidity and mortality rates were evaluated.

RESULTS

15.78% of patients had a body mass index > 35. 6.76% had chronic obstructive pulmonary disease, 6.76% had cardiac disease, 10.52% had diabetes and 4.51% had sepsis. American Society of Anesthesiology scores were I in 54.13%, II in 35.33%, III in 6.01% and IV in 4.51% of the patients. 27.81% of patients were diagnosed during surgery. The perforation site was the gallbladder fundus in 69.17%, body in 17.30%, Hartman's pouch in 10.53% and cystic duct in 3% of patients. Treatment modalities were laparoscopic cholecystectomy in 82.71%, open cholecystectomy in 3%, percutaneous drainage catheters + laparoscopic cholecystectomy in 3%, laparoscopic cholecystectomy + fistula repair in 10.53% and open cholecystectomy + fistula repair in 0.75% of patients. Mean length of hospital stay was 1.69 days. Mortality and morbidity rates were 8.27% and 10.52%, respectively. Histopathology results were acute cholecystitis in 69.93%, chronic cholecystitis in 20.30% and acute exacerbation over chronic cholecystitis in 9.77% of patients.

CONCLUSIONS

Appropriate classification and management of perforated cholecystitis is essential. Laparoscopic cholecystectomy is a safe and feasible method to decrease morbidity in gallbladder perforations.

摘要

引言

胆囊穿孔(GBP)是一种罕见疾病,具有潜在的死亡率。既往系列报道的发病率约为2%-11%,对外科医生而言,它仍然是一个重大问题。

目的

介绍我们在胆囊穿孔方面的临床经验。

材料与方法

回顾性分析2010年至2016年间接受手术治疗胆结石的2754例患者的病历。其中133例患者发生胆囊穿孔。对年龄、性别、症状出现时间、诊断方法、手术治疗、发病率和死亡率进行评估。

结果

15.78%的患者体重指数>35。6.76%的患者患有慢性阻塞性肺疾病,6.76%的患者患有心脏病,10.52%的患者患有糖尿病,4.51%的患者患有败血症。美国麻醉医师协会(ASA)分级:I级占54.13%,II级占35.33%,III级占6.01%,IV级占4.51%。27.81%的患者在手术中被诊断。穿孔部位:胆囊底部占69.17%,体部占17.30%,Hartman袋占10.53%,胆囊管占3%。治疗方式:82.71%的患者行腹腔镜胆囊切除术,3%的患者行开腹胆囊切除术,3%的患者行经皮引流管 + 腹腔镜胆囊切除术,10.53%的患者行腹腔镜胆囊切除术 + 瘘修补术,0.75%的患者行开腹胆囊切除术 + 瘘修补术。平均住院时间为1.69天。死亡率和发病率分别为8.27%和10.52%。组织病理学结果:急性胆囊炎占69.93%,慢性胆囊炎占20.30%,慢性胆囊炎急性加重占9.77%。

结论

对穿孔性胆囊炎进行恰当的分类和处理至关重要。腹腔镜胆囊切除术是降低胆囊穿孔发病率的一种安全可行的方法。

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