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[产前超声诊断是否改变了肠闭锁的预后?一项多中心研究的结果]

[Has prenatal ultrasonic diagnosis modified the prognosis of intestinal atresia? Results of a multicenter study].

作者信息

Battin J, Drossart F, Bucco P, Maugey B, Salamon R

出版信息

J Genet Hum. 1985 Dec;33(5):463-8.

PMID:2936867
Abstract

A multicentric investigation concerning intestinal atresia diagnosed in french university hospitals from 1979 to 1983, has been done. Out of 96 exploitable cases coming from 8 centers, 28 correspond to intestinal atresias which had subject to prenatal echographic diagnosis: that is 29%. 15 of the 96 atresias were affected with trisomy. 21 which had not been recognised in utero. Concerning the isolated duodenal atresia, not accompanied by any other malformation, the post surgical evolution has been appreciated during the 12 months following the surgical operation. There was no statistically significant difference, in favour of the group of children whose malformation has been recognised in utero, concerning the number of post surgical complications. This result, apparently deceitful, can be explained by the early management of these malformations in specialised centers which have participated in this study.

摘要

一项关于1979年至1983年在法国大学医院诊断出的肠道闭锁的多中心调查已经完成。在来自8个中心的96例可利用病例中,有28例对应于产前超声诊断出的肠道闭锁:即29%。96例闭锁中有15例患有三体综合征。21例在子宫内未被识别。关于孤立性十二指肠闭锁,不伴有任何其他畸形,在手术后12个月内评估了手术后期的进展。在术后并发症数量方面,对于子宫内已识别畸形的儿童组,没有统计学上的显著差异。这个明显令人困惑的结果可以通过参与本研究的专业中心对这些畸形的早期处理来解释。

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