Kalveram K J, Kästner H, Forck G
Z Hautkr. 1986 Jan;61(1-2):75-8, 81.
We report on veterinarians showing itching, swelling, and urticaria on hands and arms after contact with amniotic fluid of cows and/or pigs. Scratch tests with the corresponding fluid gave positive results. RAST investigations were done with self-prepared allergen discs. In all 6 cases, the RAST on amniotic fluid was positive, correlating well with the results of the skin tests. RAST tests on sera from the cattle were positive, too, whereas tests on the epithelia remained negative. Our findings show that the allergen causing contact urticaria is a compound of amniotic fluid and serum but not of the epithelia of these animals. Thus we can conclude that sensitized veterinarians do not have to avoid all contact with these species, but we recommend special protection.
我们报告了一些兽医在接触牛和/或猪的羊水后，手部和手臂出现瘙痒、肿胀和荨麻疹的情况。用相应液体进行的划痕试验结果呈阳性。使用自行制备的过敏原盘进行了放射变应原吸附试验（RAST）。在所有6例病例中，羊水的RAST试验呈阳性，与皮肤试验结果相关性良好。牛血清的RAST试验也呈阳性，而上皮细胞的试验仍为阴性。我们的研究结果表明，引起接触性荨麻疹的过敏原是羊水和血清的复合物，而非这些动物的上皮细胞。因此我们可以得出结论，致敏的兽医不必避免与这些物种的所有接触，但我们建议采取特殊防护措施。
