通过铜催化的芳基重氮四氟硼酸盐、DABCO·(SO)和 N-氯代胺的偶联反应合成芳香族磺酰胺。
Synthesis of Aromatic Sulfonamides through a Copper-Catalyzed Coupling of Aryldiazonium Tetrafluoroborates, DABCO·(SO), and N-Chloroamines.
机构信息
College of Science, Hunan Agricultural University , Changsha 410128, China.
Department of Chemistry, Fudan University , 220 Handan Road, Shanghai 200433, China.
出版信息
Org Lett. 2018 Feb 16;20(4):1167-1170. doi: 10.1021/acs.orglett.8b00093. Epub 2018 Jan 26.
A copper-catalyzed aminosulfonylation of aryldiazonium tetrafluoroborates, DABCO·(SO), and N-chloroamines is described. This coupling reaction provides an efficient and simple approach to a wide range of sulfonamides in moderate to good yields under mild conditions. Mechanistic investigation suggests that a radical process and transition-metal catalysis are merged in this tandem reaction.
本文描述了一种铜催化的芳基重氮四氟硼酸盐、DABCO·(SO)和 N-氯代胺的氨基磺酰化反应。该偶联反应在温和条件下以中等至良好的收率高效、简便地合成了一系列磺酰胺类化合物。反应机理研究表明，该串联反应涉及自由基过程和过渡金属催化过程的协同作用。
Zotero 插件