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右旋糖酐铁所致全血细胞减少症

Pancytopenia caused by iron-dextran.

作者信息

Hurvitz H, Kerem E, Gross-Kieselstein E, Brand A, Branski D

出版信息

Arch Dis Child. 1986 Feb;61(2):194-6. doi: 10.1136/adc.61.2.194.

Abstract

Pancytopenia after intramuscular iron-dextran treatment occurred in an infant with Down's syndrome. Haematological abnormalities recurred on subsequent challenge. Positive migration inhibiting factor and mast cell degranulation tests support an allergic pathogenesis for the pancytopenia. These side effects have not been reported previously.

摘要

一名唐氏综合征婴儿在接受肌肉注射右旋糖酐铁治疗后出现全血细胞减少。在随后的激发试验中血液学异常复发。阳性迁移抑制因子和肥大细胞脱颗粒试验支持全血细胞减少的过敏发病机制。这些副作用以前尚未见报道。

相似文献

1
Pancytopenia caused by iron-dextran.右旋糖酐铁所致全血细胞减少症
Arch Dis Child. 1986 Feb;61(2):194-6. doi: 10.1136/adc.61.2.194.
3
Aplastic anemia in Down's syndrome.
Pediatrics. 1981 Jun;67(6):896-7.
5
Adverse effects of intramuscular iron injection.肌肉注射铁剂的不良反应。
Acta Haematol. 1982;68(4):341-2. doi: 10.1159/000207007.
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Iron and infection.
Br Med J (Clin Res Ed). 1988 Jun 18;296(6638):1736. doi: 10.1136/bmj.296.6638.1736-a.

本文引用的文献

2
Sarcoma after intramuscular iron injection.肌肉注射铁剂后发生的肉瘤。
Br Med J. 1976 Jun 19;1(6024):1508-9. doi: 10.1136/bmj.1.6024.1508-a.
3
Allergic purpura following intravenous administration of iron dextran.
Acta Haematol. 1979;62(3):178. doi: 10.1159/000207567.
4
Letter: Neutropenia and iron therapy.
Lancet. 1976 Aug 7;2(7980):310. doi: 10.1016/s0140-6736(76)90759-5.

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