Stanĕk R, Veselský L, Dostál J, Sedláková E
Arch Androl. 1985;15(1):29-32. doi: 10.3109/01485018508986888.
Boar seminal plasma and seminal vesicle fluid inhibited mitogen-induced blastic transformation of porcine lymphocytes. Chromatographic separation of seminal vesicle fluid on Sephadex G-100 yielded four fractions. Only the SV-1 fraction displayed significant inhibition of blastic transformation. The results demonstrated that the immunosuppressive factor(s) in seminal plasma is secreted in seminal vesicles. Increased inhibition of blastic transformation of lymphocytes stimulated with pokeweed mitogen indicates that seminal plasma inhibits mainly B lymphocytes. Both seminal plasma and seminal vesicle fluid inhibited unstimulated lymphocytes.
公猪精浆和精囊液可抑制有丝分裂原诱导的猪淋巴细胞的母细胞转化。在葡聚糖凝胶G - 100上对精囊液进行色谱分离得到四个组分。只有SV - 1组分对母细胞转化表现出显著抑制作用。结果表明,精浆中的免疫抑制因子是由精囊分泌的。用商陆有丝分裂原刺激的淋巴细胞母细胞转化抑制作用增强,表明精浆主要抑制B淋巴细胞。精浆和精囊液均可抑制未受刺激的淋巴细胞。