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[乳糜泻——儿童及成人疾病:症状、疾病并发症、风险群体及合并症]

[Celiac disease - disease of children and adults: symptoms, disease complications, risk groups and comorbidities].

作者信息

Majsiak Emilia, Cichoż-Lach Halina, Gubska Olena, Cukrowska Bożena

机构信息

Polish-Ukrainian Fundation of Medicine Development, Lublin, Poland.

Chair and Department of Gastroenterology with Endoscopy Division, Medical University, Lublin, Poland.

出版信息

Pol Merkur Lekarski. 2018 Jan 23;44(259):31-35.

Abstract

About 1% of human population suffers from celiac disease (CD) and it is one of the most commonly diagnosed autoimmune disorders. Until recently it was believed that CD affects mainly children, but as the newest studies show, up to 60% recently diagnosed patients are adults, often over the age of 60. CD's medical signs are nonspecific. Atypical course of the disease with extraintestinal symptoms is being increasingly observed. The disease may also be asymptomatic over many years. The studies show that the average diagnosis of CD takes more than 10 years since the first symptoms appear. Nonspecific medical signs cause undiagnosed patients suffering from CD to visit gastroenterologists, endocrinologists, allergists, gynaecologists and other medical specialists. However, most frequently general practitioners have the first encounter with patients suffering from CD, therefore they are able to recognize symptoms of the disease at the earliest and refer the patient to a gastroenterologist. Early diagnosis and beginning of the treatment reduce complications of untreated CD. The aim of this paper is to show general practitioners symptoms, disease complications, risk groups and comorbidities of CD.

摘要

约1%的人口患有乳糜泻(CD),它是最常被诊断出的自身免疫性疾病之一。直到最近,人们还认为乳糜泻主要影响儿童,但最新研究表明,最近确诊的患者中高达60%是成年人,且往往超过60岁。乳糜泻的医学体征不具有特异性。越来越多地观察到该疾病伴有肠外症状的非典型病程。这种疾病也可能多年无症状。研究表明,自首次出现症状起,乳糜泻的平均诊断时间超过10年。非特异性医学体征导致患有乳糜泻却未被诊断的患者去看胃肠病学家、内分泌学家、过敏症专科医生、妇科医生和其他医学专家。然而,全科医生最常首先接触到患有乳糜泻的患者,因此他们能够最早识别出该疾病的症状并将患者转诊给胃肠病学家。早期诊断和开始治疗可减少未经治疗的乳糜泻的并发症。本文的目的是向全科医生展示乳糜泻的症状、疾病并发症、风险群体和合并症。

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