线粒体自噬：Vps13D 介导的线粒体分裂和自噬体清除。
Mitophagy: Vps13D Couples Mitochondrial Fission and Autophagic Clearance.
机构信息
National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, P.R. China.
National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, P.R. China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, P.R. China.
出版信息
Curr Biol. 2018 Jan 22;28(2):R66-R68. doi: 10.1016/j.cub.2017.12.017.
Mitophagy maintains mitochondrial homeostasis and cell health. A new study demonstrates that the ubiquitin-binding protein Vps13D functions downstream of the fission factor Drp1 to control mitochondrial size and autophagic clearance in Drosophila midgut cells.
线粒体自噬维持线粒体的内稳态和细胞健康。一项新的研究表明，泛素结合蛋白 Vps13D 作为分裂因子 Drp1 的下游因子发挥作用，以控制果蝇中肠细胞中线粒体的大小和自噬清除。
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