Eizirik D L, Boschero A C, Migliorini R H
Braz J Med Biol Res. 1985;18(2):233-5.
The streptozotocin (STZ)-induced inhibition of insulin release by isolated islets was measured in islets of rats previously adapted to either a high-protein (HP) or a balanced control diet. Islets from rats adapted to an HP diet showed decreased susceptibility to the inhibitory effect of STZ on insulin release. The data suggest that the beta cells from rats adapted to a high-protein diet have an increased resistance to the deleterious effects of STZ. These results are consistent with in vivo data (D.L. Eizirik and R.H. Migliorini, Diabetes, 33: 383-388, 1984).
在先前适应高蛋白（HP）或均衡对照饮食的大鼠胰岛中，测定链脲佐菌素（STZ）诱导的分离胰岛胰岛素释放抑制情况。适应高蛋白饮食的大鼠的胰岛对STZ对胰岛素释放的抑制作用的敏感性降低。数据表明，适应高蛋白饮食的大鼠的β细胞对STZ的有害作用具有增强的抗性。这些结果与体内数据一致（D.L. Eizirik和R.H. Migliorini，《糖尿病》，33: 383 - 388，1984）。
