Ishikawa Haruna, Guo Xiaoxu, Sugawara Saeko, Iwagaki Yui, Yamamoto Kazushi, Tsuduki Tsuyoshi
a Laboratory of Food and Biomolecular Science, Graduate School of Agriculture , Tohoku University , Sendai , Japan.
Biosci Biotechnol Biochem. 2018 Mar;82(3):515-524. doi: 10.1080/09168451.2018.1428788. Epub 2018 Jan 29.
We examined the effects on offspring of ingestion of the 1975 Japanese diet during pregnancy and lactation and after weaning in mice. Pregnant dams were divided into groups that were fed the Japanese diet or a control diet and raised until offspring were weaned. The offspring after weaning were further divided into groups that were raised on the Japanese diet or the control diet. Ingestion of the Japanese diet after weaning suppressed accumulation of visceral fat in offspring, and reduced the amount of lipids in serum and liver. This effect was weakened if the Japanese diet was only ingested during pregnancy and lactation. Therefore, it was suggested that ingestion of the Japanese diet of mothers during pregnancy and lactation weakens the lipid accumulation inhibitory effect of the Japanese diet in children.
我们研究了孕期、哺乳期及断奶后小鼠摄入1975年日本饮食对其后代的影响。怀孕的母鼠被分为两组，分别喂食日本饮食或对照饮食，直至后代断奶。断奶后的后代进一步分为两组，分别喂食日本饮食或对照饮食。断奶后摄入日本饮食可抑制后代内脏脂肪蓄积，并减少血清和肝脏中的脂质含量。若仅在孕期和哺乳期摄入日本饮食，这种效果会减弱。因此，提示孕期和哺乳期母亲摄入日本饮食会削弱日本饮食对儿童脂质蓄积的抑制作用。
