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用于微创乳腺肿瘤消融的优化双槽微同轴天线的计算有限元模型及猪乳腺验证:温度、病变大小和电压驻波比的理论与实验比较,初步数据

Computational FEM Model, and Swine Breast Validation of an Optimized Double-Slot Microcoaxial Antenna Designed for Minimally Invasive Breast Tumor Ablation: Theoretical and Experimental Comparison of Temperature, Size of Lesion, and SWR, Preliminary Data.

作者信息

Guerrero López Geshel David, Cepeda Rubio Mario Francisco Jesús, Hernández Jácquez José Irving, Vera Hernandez Arturo, Leija Salas Lorenzo, Valdés Perezgasga Francisco, Flores García Francisco

机构信息

División de Estudios de Posgrado e Investigación, Tecnológico Nacional de México, Instituto Tecnológico de la Laguna, Blvd. Revolución, Esq. Calzad. Instituto Tecnológico de la Laguna, Zona Centro, 27000 Torreón, COAH, Mexico.

Sección de Bioelectrónica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Ciudad de México, Mexico.

出版信息

Comput Math Methods Med. 2017;2017:1562869. doi: 10.1155/2017/1562869. Epub 2017 Dec 10.

DOI:10.1155/2017/1562869
PMID:29375651
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5742501/
Abstract

Malignant neoplasms are one of the principal world health concerns and breast cancer is the most common type of cancer in women. Advances in cancer detection technologies allow treating it in early stages; however, it is necessary to develop treatments which carry fewer complications and aesthetic repercussions. This work presents a feasibility study for the use of microwave ablation as a novel technique for breast cancer treatment. A microwave applicator design is also being proposed for this purpose. The coupling of the designed antenna was predicted with computer simulation. The standing wave ratio obtained through simulation was 1.87 and the result of experimental validation was 1.04. The optimized antenna has an optimal coupling (SWR = 1.04) so ablation temperatures can be achieved in a relatively short time using low power. Varying the time and power, the heating pattern can be changed to treat different tumors. However, as some discrepancies are still present, a deeper study of the dielectric properties and their variation with temperature is required.

摘要

恶性肿瘤是全球主要的健康问题之一,乳腺癌是女性中最常见的癌症类型。癌症检测技术的进步使得能够在早期阶段对其进行治疗;然而,有必要开发出并发症和美学影响较少的治疗方法。这项工作提出了一项关于使用微波消融作为乳腺癌治疗新技术的可行性研究。为此还提出了一种微波施加器设计。通过计算机模拟预测了所设计天线的耦合情况。模拟得到的驻波比为1.87,实验验证结果为1.04。优化后的天线具有最佳耦合(驻波比 = 1.04),因此可以使用低功率在相对较短的时间内达到消融温度。通过改变时间和功率,可以改变加热模式以治疗不同的肿瘤。然而,由于仍然存在一些差异,需要对介电特性及其随温度的变化进行更深入的研究。

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A retrospective comparison of microwave ablation vs. radiofrequency ablation for colorectal cancer hepatic metastases.微波消融与射频消融治疗结直肠癌肝转移的回顾性比较
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