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脂质体布比卡因用于烧伤患者术后供皮区疼痛的管理:来自两家机构的病例系列研究

Liposomal bupivacaine for the management of postsurgical donor site pain in patients with burn injuries: a case series from two institutions.

作者信息

Dissanaike Sharmila, McCauley Jayne, Alphonso Carlo

机构信息

Department of Surgery Texas Tech University Health Sciences Center Lubbock Texas.

US Army Institute of Surgical Research Fort Sam Houston Texas.

出版信息

Clin Case Rep. 2017 Dec 5;6(1):129-135. doi: 10.1002/ccr3.1292. eCollection 2018 Jan.

DOI:10.1002/ccr3.1292
PMID:29375852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5771936/
Abstract

Donor site pain associated with skin graft procedures is frequently intense and difficult to treat. Liposomal bupivacaine, a prolonged-release local anesthetic indicated for single-dose administration to produce postsurgical analgesia, may be a viable option in managing donor site pain.

摘要

与皮肤移植手术相关的供区疼痛通常很剧烈且难以治疗。脂质体布比卡因是一种长效局部麻醉剂,适用于单剂量给药以产生术后镇痛效果,它可能是管理供区疼痛的一个可行选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1a/5771936/f61608ae37ed/CCR3-6-129-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1a/5771936/f61608ae37ed/CCR3-6-129-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f1a/5771936/f61608ae37ed/CCR3-6-129-g001.jpg

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Anesth Analg. 2017 Jan;124(1):308-335. doi: 10.1213/ANE.0000000000001581.
2
Sedation and Analgesia for Dressing Change: A Survey of American Burn Association Burn Centers.换药时的镇静与镇痛:美国烧伤协会烧伤中心调查
J Burn Care Res. 2017 Jan/Feb;38(1):e48-e54. doi: 10.1097/BCR.0000000000000423.
3
Time to Analgesia Onset and Pharmacokinetics After Separate and Combined Administration of Liposome Bupivacaine and Bupivacaine HCl: Considerations for Clinicians.
脂质体布比卡因与盐酸布比卡因单独及联合给药后的镇痛起效时间和药代动力学:临床医生需考虑的因素
Open Orthop J. 2016 Apr 12;10:94-104. doi: 10.2174/1874325001610010094. eCollection 2016.
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Psychometric Testing of the Defense and Veterans Pain Rating Scale (DVPRS): A New Pain Scale for Military Population.国防与退伍军人疼痛评定量表(DVPRS)的心理测量测试:一种针对军人群体的新型疼痛量表。
Pain Med. 2016 Aug;17(8):1505-19. doi: 10.1093/pm/pnw105. Epub 2016 Jun 6.
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The management of pain associated with wound care in severe burn patients in Spain.西班牙严重烧伤患者伤口护理相关疼痛的管理
Int J Burns Trauma. 2016 Jan 10;6(1):1-10. eCollection 2016.
6
Reducing Opioid Adverse Events: A Safe Way to Improve Outcomes.减少阿片类药物不良事件:改善治疗结果的安全途径。
Surg Technol Int. 2016 Apr;28:101-9.
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Impact of volume expansion on the efficacy and pharmacokinetics of liposome bupivacaine.容量扩张对脂质体布比卡因疗效和药代动力学的影响。
Local Reg Anesth. 2015 Dec 7;8:105-11. doi: 10.2147/LRA.S88685. eCollection 2015.
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