Fragulidis Georgios P, Pantiora Eirini V, Kontis Elissaios A, Primetis Elias, Polydorou Andreas, Karvouni Eleni, Polymeneas George
2nd Department of Surgery, ARETAIEIO Hospital, National and Kapodistrian University of Athens School of Medicine.
1st Department of Radiology, ARETAIEIO Hospital, National and Kapodistrian University of Athens School of Medicine.
Cureus. 2017 Nov 20;9(11):e1863. doi: 10.7759/cureus.1863.
Biliary mucinous cystic neoplasms of the liver are rare cystic tumors comprising less than 5% of the liver cystic neoplasms. These tumors demonstrate a female predominance and entail a risk of malignant transformation. We present a 56-year-old female patient with a multiloculated liver cystic lesion measuring 22 cm who underwent a cystectomy with en bloc resection of the liver segments II, III, and cholecystectomy. Serum cancer antigen 19.9 was 4,122.00 U/ml, supporting the diagnosis of a biliary cystic tumor. The cytology of the cystic fluid was negative for malignancy and intracystic fluid cancer antigen 19.9 level was measured over 12,000.00 U/l. The patient is free of recurrence at one-year follow up. Although a rare entity, the biliary mucinous cystic neoplasms should be considered in the differential diagnosis in the patients with liver cystic tumors. The appropriate management with complete surgical resection with negative margins is recommended given the risk of recurrence and malignant transformation.
肝脏黏液性囊性肿瘤是罕见的囊性肿瘤，占肝脏囊性肿瘤的比例不到5%。这些肿瘤以女性居多，并且存在恶变风险。我们报告了一名56岁女性患者，其肝脏有一个22厘米的多房性囊性病变，接受了囊肿切除术，同时整块切除了肝段II、III，并进行了胆囊切除术。血清癌抗原19.9为4122.00 U/ml，支持胆囊囊性肿瘤的诊断。囊液细胞学检查未发现恶性肿瘤，囊内液癌抗原19.9水平超过12000.00 U/l。患者在一年随访中无复发。尽管是罕见疾病，但在肝脏囊性肿瘤患者的鉴别诊断中应考虑黏液性囊性肿瘤。鉴于存在复发和恶变风险，建议进行切缘阴性的完整手术切除。
