Galaktionov V G, Anfalova T V, Lutsan N I, Golenishchev V Iu, Poznakhirev P R
Genetika. 1986 Feb;22(2):244-52.
H-2 complex control of interaction between macrophages and thymocytes during induction of T-cell effectors GVH was studied. Intensity of the local GVH reaction was evaluated by the index of the lymph nodes enlargement. Genes of the H-2 system control interaction of macrophages with thymocytes during the formation of T-cell effectors GVH. H-2K subregion genes identity of interacting cells was necessary and sufficient for the effective induction of T-effectors GVH. I and D region differences did not affect the formation of T-cells inducing GVH.
研究了H-2复合体在T细胞效应物GVH诱导过程中对巨噬细胞与胸腺细胞相互作用的控制。通过淋巴结肿大指数评估局部GVH反应的强度。H-2系统的基因在T细胞效应物GVH形成过程中控制巨噬细胞与胸腺细胞的相互作用。相互作用细胞的H-2K亚区基因相同对于有效诱导GVH的T效应物是必要且充分的。I区和D区的差异不影响诱导GVH的T细胞的形成。