Wattier Rachel L, Ramirez-Avila Lynn
Department of Pediatrics, Division of Infectious Diseases and Global Health, University of California-San Francisco, 550 16th St, 4th Floor, Box 0434, San Francisco, CA 94143, USA.
J Fungi (Basel). 2016 Jun 13;2(2):19. doi: 10.3390/jof2020019.
Invasive aspergillosis (IA) is a disease of increasing importance in pediatrics due to growth of the immunocompromised populations at risk and improvements in long-term survival for many of these groups. While general principles of diagnosis and therapy apply similarly across the age spectrum, there are unique considerations for clinicians who care for children and adolescents with IA. This review will highlight important differences in the epidemiology, clinical manifestations, diagnosis, and therapy of pediatric IA.
侵袭性曲霉病(IA)在儿科中的重要性日益增加,这是由于免疫功能低下的高危人群不断增多,且其中许多群体的长期生存率有所提高。虽然诊断和治疗的一般原则在各个年龄段大致相同,但对于照顾患有IA的儿童和青少年的临床医生来说,仍有一些独特的考虑因素。本综述将重点介绍儿童IA在流行病学、临床表现、诊断和治疗方面的重要差异。