Stiell Ian G, Perry Jeffrey J, Brehaut Jamie, Brown Erica, Curran Janet A, Emond Marcel, Hohl Corinne, Taljaard Monica, McRae Andrew D
*Department of Emergency Medicine,University of Ottawa,Ottawa,ON.
†Clinical Epidemiology Program,Ottawa Hospital Research Institute,Ottawa,ON.
CJEM. 2018 May;20(3):448-452. doi: 10.1017/cem.2017.433. Epub 2018 Jan 30.
The objective of Panel 2b was to present an overview of and recommendations for the conduct of implementation trials and multicentre studies in emergency medicine.
Panel members engaged methodologists to discuss the design and conduct of implementation and multicentre studies. We also conducted semi-structured interviews with 37 Canadian adult and pediatric emergency medicine researchers to elicit barriers and facilitators to conducting these kinds of studies.
Responses were organized by themes, and, based on these responses, recommendations were developed and refined in an iterative fashion by panel members.
We offer eight recommendations to facilitate multicentre clinical and implementation studies, along with guidance for conducting implementation research in the emergency department. Recommendations for multicentre studies reflect the importance of local study investigators and champions, requirements for research infrastructure and staffing, and the cooperation and communication between the coordinating centre and participating sites.
2b小组的目的是概述急诊医学中实施试验和多中心研究的开展情况并提出建议。
小组成员邀请方法学家讨论实施研究和多中心研究的设计与开展。我们还对37名加拿大成人及儿科急诊医学研究人员进行了半结构化访谈，以找出开展这类研究的障碍和促进因素。
根据主题对回复进行了整理，并在此基础上，小组成员以迭代方式制定并完善了建议。
我们提出了八项建议，以促进多中心临床研究和实施研究，同时提供了在急诊科开展实施研究的指导。多中心研究的建议反映了当地研究调查人员和倡导者的重要性、研究基础设施和人员配备的要求，以及协调中心与参与站点之间的合作与沟通。
