Guedes Bruno Fukelmann, Souza Marcio Nattan Portes, Barbosa Breno José Alencar Pires, Frassetto Fernando Pereira, Lucato Leandro Tavares, Ono Carla Rachel, Castro Luiz Henrique Martins, Nitrini Ricardo, Simabukuro Mateus Mistieri
Neurology Department, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil.
Pathology Department, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil.
Pract Neurol. 2018 Aug;18(4):306-310. doi: 10.1136/practneurol-2017-001771. Epub 2018 Jan 29.
A young woman presented with primary amenorrhoea, progressive haemiparesis, visual disturbance, dementia and focal motor seizures. Investigations showed hypopituitarism, unilateral cerebral atrophy and inflamed cerebrospinal fluid. A trans-sphenoidal biopsy gave a unifying diagnosis of a pituitary germinoma.
