'Et tu, inhibitor?': the potential for HIV inhibitors to prime P-gp-mediated chemoresistance in cancer.
作者信息
Shull Austin Y, Farrell Christopher L
机构信息
Department of Biology, Presbyterian College, Clinton, SC 29325, USA.
Department of Pharmaceutical & Administrative Sciences, Presbyterian College School of Pharmacy, Clinton, SC 29325, USA.
出版信息
Future Sci OA. 2017 Nov 23;4(2):FSO269. doi: 10.4155/fsoa-2017-0134. eCollection 2018 Feb.
Abstract
摘要
相似文献
1
'Et tu, inhibitor?': the potential for HIV inhibitors to prime P-gp-mediated chemoresistance in cancer.“你也一样，抑制剂？”：HIV抑制剂引发癌症中P-糖蛋白介导的化疗耐药性的可能性
Future Sci OA. 2017 Nov 23;4(2):FSO269. doi: 10.4155/fsoa-2017-0134. eCollection 2018 Feb.
2
Increased expression and function of P-glycoprotein in peripheral blood CD56+ cells is associated with the chemoresistance of non-small-cell lung cancer.外周血 CD56+ 细胞中 P-糖蛋白表达和功能的增加与非小细胞肺癌的化疗耐药性有关。
Cancer Chemother Pharmacol. 2012 Sep;70(3):365-72. doi: 10.1007/s00280-012-1915-x. Epub 2012 Jul 11.
3
Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation.衣霉素通过抑制 N-糖基化特异性加重内质网应激并克服多药耐药胃癌细胞的化疗耐药性。
J Exp Clin Cancer Res. 2018 Nov 9;37(1):272. doi: 10.1186/s13046-018-0935-8.
4
Tariquidar sensitizes multiple myeloma cells to proteasome inhibitors via reduction of hypoxia-induced P-gp-mediated drug resistance.塔里喹达通过降低缺氧诱导的P-糖蛋白介导的耐药性，使多发性骨髓瘤细胞对蛋白酶体抑制剂敏感。
Leuk Lymphoma. 2017 Dec;58(12):2916-2925. doi: 10.1080/10428194.2017.1319052. Epub 2017 May 16.
5
Twist confers chemoresistance to anthracyclines in bladder cancer through upregulating P-glycoprotein.Twist 通过上调 P-糖蛋白赋予膀胱癌对蒽环类药物的耐药性。
Chemotherapy. 2012;58(4):264-72. doi: 10.1159/000341860. Epub 2012 Sep 12.
6
Quantitative assessment of HIV-1 protease inhibitor interactions with drug efflux transporters in the blood-brain barrier.HIV-1蛋白酶抑制剂与血脑屏障中药物外排转运体相互作用的定量评估。
Pharm Res. 2005 Aug;22(8):1259-68. doi: 10.1007/s11095-005-5271-y. Epub 2005 Aug 3.
7
In silico identified targeted inhibitors of P-glycoprotein overcome multidrug resistance in human cancer cells in culture.计算机模拟鉴定的 P-糖蛋白靶向抑制剂可克服人癌细胞培养中的多药耐药性。
Pharmacol Res Perspect. 2015 Oct;3(5):e00170. doi: 10.1002/prp2.170. Epub 2015 Aug 10.
8
Co-treatment With HIV Protease Inhibitor Nelfinavir Greatly Increases Late-phase Apoptosis of Drug-resistant KBV20C Cancer Cells Independently of P-Glycoprotein Inhibition.与HIV蛋白酶抑制剂奈非那韦联合治疗可显著增加耐药KBV20C癌细胞的晚期凋亡，且与P-糖蛋白抑制无关。
Anticancer Res. 2019 Jul;39(7):3757-3765. doi: 10.21873/anticanres.13524.
9
Inhibitory effect of human immunodeficiency virus protease inhibitors on multidrug resistance transporter P-glycoproteins.人类免疫缺陷病毒蛋白酶抑制剂对多药耐药转运蛋白P-糖蛋白的抑制作用。
Biol Pharm Bull. 2000 Dec;23(12):1528-31. doi: 10.1248/bpb.23.1528.
10
P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?P-糖蛋白和转运体MRP1降低HIV蛋白酶抑制剂在CD4细胞中的摄取：加速病毒耐药的可能性？
AIDS. 2001 Jul 27;15(11):1353-8. doi: 10.1097/00002030-200107270-00004.
本文引用的文献
1
Medication usage change in older people (65+) in England over 20 years: findings from CFAS I and CFAS II.20 年来英格兰（65 岁以上）老年人用药习惯的变化：来自 CFAS I 和 CFAS II 的研究结果。
Age Ageing. 2018 Mar 1;47(2):220-225. doi: 10.1093/ageing/afx158.
2
The molecular mechanisms of chemoresistance in cancers.癌症中化疗耐药的分子机制。
Oncotarget. 2017 Jul 6;8(35):59950-59964. doi: 10.18632/oncotarget.19048. eCollection 2017 Aug 29.
3
The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors.P-糖蛋白和乳腺癌耐药蛋白对一组MEK抑制剂脑药代动力学和药效学的影响。
Int J Cancer. 2018 Jan 15;142(2):381-391. doi: 10.1002/ijc.31052. Epub 2017 Oct 4.
4
Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents.克服ABC转运蛋白介导的多药耐药性：酪氨酸激酶抑制剂作为多靶点药物的双重作用。
Eur J Med Chem. 2017 Dec 15;142:271-289. doi: 10.1016/j.ejmech.2017.07.062. Epub 2017 Aug 3.
5
Nilotinib reverses ABCB1/P-glycoprotein-mediated multidrug resistance but increases cardiotoxicity of doxorubicin in a MDR xenograft model.尼罗替尼可逆转ABCB1/P-糖蛋白介导的多药耐药性，但在多药耐药异种移植模型中会增加阿霉素的心脏毒性。
Toxicol Lett. 2016 Sep 30;259:124-132. doi: 10.1016/j.toxlet.2016.07.710. Epub 2016 Aug 1.
6
HIV-1 Alters Intestinal Expression of Drug Transporters and Metabolic Enzymes: Implications for Antiretroviral Drug Disposition.HIV-1改变药物转运体和代谢酶的肠道表达：对抗逆转录病毒药物处置的影响。
Antimicrob Agents Chemother. 2016 Apr 22;60(5):2771-81. doi: 10.1128/AAC.02278-15. Print 2016 May.
7
Trends in Prescription Drug Use Among Adults in the United States From 1999-2012.1999 - 2012年美国成年人处方药使用趋势
JAMA. 2015 Nov 3;314(17):1818-31. doi: 10.1001/jama.2015.13766.
8
Providing a molecular mechanism for P-glycoprotein; why would I bother?为P-糖蛋白提供一种分子机制；我为什么要费这个劲呢？
Biochem Soc Trans. 2015 Oct;43(5):995-1002. doi: 10.1042/BST20150131.
9
Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.抑制ABCB1可克服非小细胞肺癌中的癌症干细胞样特性及对MET抑制剂的获得性耐药。
Mol Cancer Ther. 2015 Nov;14(11):2433-40. doi: 10.1158/1535-7163.MCT-15-0050. Epub 2015 Sep 8.
10
Lgr5 promotes cancer stemness and confers chemoresistance through ABCB1 in colorectal cancer.Lgr5 通过 ABCB1 在结直肠癌中促进癌症干细胞特性并赋予化疗耐药性。
Biomed Pharmacother. 2013 Oct;67(8):791-9. doi: 10.1016/j.biopha.2013.08.001. Epub 2013 Aug 23.
Zotero 插件