MW 多瘤病毒在意大利腹泻婴儿中的研究。
MW Polyomavirus in diarrheal Italian infants.
机构信息
School of Medicine, Department of Public Health and Pediatric Sciences, University of Turin, Turin, Italy -
School of Medicine, Department of Public Health and Pediatric Sciences, University of Turin, Turin, Italy.
出版信息
Minerva Pediatr (Torino). 2023 Jun;75(3):327-330. doi: 10.23736/S2724-5276.18.04991-5. Epub 2018 Jan 29.
BACKGROUND
MXPyV, like MWPyV, was identified in stool samples from children suffering diarrhea in Mexico. In this study, we used a home-made real time PCR to investigate the presence of this novel viruses in stool specimen collected from under-five-year-old children with gastroenteritis.
METHODS
A total of 192 fecal specimens previously screened for RV, ADV, NoV, HPeV and SaV, were tested for MWPyV with Taqman real time PCR.
RESULTS
The most detected virus was NoV GII (33.8%), followed by RV (21.3%), SaV (10.9%), HPeV (8%), NoV GI (6.7%) and Adv (1%). Real time PCR detected MWPyV in 1/192 (0.5%) patients.
CONCLUSIONS
We detected MWPyV in 0.5% of fecal specimens collected from pediatric patients suffering gastroenteritis which is smaller than the previously reported in literature (4.4% in Australia and 12% Mexico).
背景
与 MWPyV 类似，MXPyV 是在墨西哥腹泻儿童的粪便样本中发现的。在这项研究中，我们使用自制的实时 PCR 来检测胃肠炎五岁以下儿童粪便样本中是否存在这种新型病毒。
方法
共检测了 192 份先前筛查 RV、ADV、NoV、HPeV 和 SaV 的粪便标本，用 Taqman 实时 PCR 检测 MWPyV。
结果
最常见的病毒是 NoV GII（33.8%），其次是 RV（21.3%）、SaV（10.9%）、HPeV（8%）、NoV GI（6.7%）和 Adv（1%）。实时 PCR 在 1/192（0.5%）患者的粪便标本中检测到 MWPyV。
结论
我们在 0.5%的胃肠炎患儿粪便标本中检测到 MWPyV，低于文献报道的（澳大利亚 4.4%，墨西哥 12%）。
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