韩国人群中嗅觉功能障碍与听力损失及发声障碍的流行病学关联：一项横断面研究。
Epidemiological association of olfactory dysfunction with hearing loss and dysphonia in the Korean population: A cross-sectional study.
作者信息
Park Jae Hong, Byeon Hyung Kwon, Park Ki Nam, Kim Jae Wook, Lee Seung Won, Han Kyung-do, Chang Jae Won, Kim Won Shik, Koh Yoon Woo, Ban Myung Jin
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Cheonan Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Seoul Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul Department of Otorhinolaryngology, Chungnam National University College of Medicine, Daejeon Department of Medicine, Graduate School, Yonsei University, Seoul, Republic of Korea.
出版信息
Medicine (Baltimore). 2017 Nov;96(47):e8890. doi: 10.1097/MD.0000000000008890.
The aim of the study is to investigate the association between olfactory dysfunction (OD), hearing loss, and dysphonia.The cross-sectional data for 17,984 adults who completed the Korea National Health and Nutrition Examination Surveys (2010-12) were analyzed. OD, hearing loss, and dysphonia were assessed using self-reporting questionnaires. The association of OD with hearing loss and dysphonia was evaluated.Hearing loss and dysphonia were significantly more prevalent in patients with OD than in those without OD (hearing loss, 28.1% vs 11.3%; dysphonia, 11.1% vs 5.9%; both P < .0001). After adjusting for confounders, including mental stress and metabolic syndrome, the risk of OD was significantly associated with hearing loss and dysphonia, and was greater in those with combined hearing loss and dysphonia than in both patients without these dysfunctions and in those with a single dysfunction (odds ratio 3.115, 95% confidence interval 1.973-4.917).OD was significantly associated with hearing loss and dysphonia.
本研究旨在调查嗅觉功能障碍（OD）、听力损失和发音障碍之间的关联。分析了17984名完成韩国国家健康与营养检查调查（2010 - 12年）的成年人的横断面数据。使用自我报告问卷评估OD、听力损失和发音障碍。评估了OD与听力损失和发音障碍之间的关联。与无OD的患者相比，OD患者的听力损失和发音障碍明显更为普遍（听力损失：28.1%对11.3%；发音障碍：11.1%对5.9%；两者P<0.0001）。在对包括精神压力和代谢综合征在内的混杂因素进行调整后，OD风险与听力损失和发音障碍显著相关，且合并听力损失和发音障碍的患者比无这些功能障碍的患者以及仅有单一功能障碍的患者风险更高（优势比3.115，95%置信区间1.973 - 4.917）。OD与听力损失和发音障碍显著相关。
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