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Treatment with Botulinum Toxin for Refractory Fever Caused by Severe Spasticity: A Case Series.

作者信息

Lester Jacobo, Alvarez-Resendiz Gerardo Esteban, Klériga Enrique, Videgaray Fernando, Zambito Gerardo

机构信息

Neurology/Movement Disorders, Instituto Mexicano de Neurociencias, Hospital Angeles Lomas, Huixquilucan, Estado de México, Mexico.

Anesthesiology, Hospital Angeles Lomas, Huixquilucan, Estado de México, Mexico.

出版信息

Neurol Ther. 2018 Jun;7(1):155-159. doi: 10.1007/s40120-018-0092-1. Epub 2018 Jan 30.

DOI:10.1007/s40120-018-0092-1
PMID:29383493
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5990504/
Abstract

INTRODUCTION

Brain and spinal cord injuries may cause very severe spasticity that occasionally may be associated with persistent fever.

CASE SERIES

We present 14 patients with spasticity and persistent fever, treated with botulinum toxin type A. Their spasticity improved and the fever resolved within a period no greater than 48 h. In all cases, infectious and other non-infectious causes were ruled out.

CONCLUSIONS

When sustained tonic muscular activity is associated with a significant increase in body temperature and is refractory to the usual drugs used for hyperpyrexia, type A botulinum toxin may be an effective treatment option to control both spasticity and fever.

摘要

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引用本文的文献

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Efficacy and Safety of Botulinum Toxin Type A in Spasticity Caused by Spinal Cord Injury: A Randomized, Controlled Trial.
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Dry needling technique decreases spasticity and improves general functioning in incomplete spinal cord injury: A case report.
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