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内镜下使用管腔对接金属支架治疗胰腺壁内坏死性病变后发生念珠菌血症。

Candidemia after endoscopic therapy with lumen-apposing metal stent for pancreatic walled-off necrosis.

作者信息

Pavic Tajana, Hrabar Davor, Kralj Dominik, Lerotic Ivan, Ogresta Doris

机构信息

Department of Gastroenterology and Hepatology, Clinical Hospital Center Sestre Milosrdnice, School of Medicine, University of Zagreb, 10000, Zagreb, Croatia.

出版信息

Clin J Gastroenterol. 2018 Jun;11(3):206-211. doi: 10.1007/s12328-018-0823-y. Epub 2018 Jan 30.

DOI:10.1007/s12328-018-0823-y
PMID:29383496
Abstract

Necrotizing pancreatitis remains a challenging and unpredictable condition accompanied by various complications. Endoscopic ultrasound-guided transmural drainage and necrosectomy have become the standard treatment for patients with walled-off necrosis (WON). Endoscopic therapy via lumen-apposing metal stents (LAMS) with large diameters has shown success in the management of pancreatic fluid collections, but there are few data on specific complications of that therapy. We report a case of infected WON and concomitant fungemia following LAMS placement and necrosectomy. In addition, a systematic literature review of current related studies has been provided.

摘要

坏死性胰腺炎仍然是一种具有挑战性且不可预测的疾病,并伴有各种并发症。内镜超声引导下经壁引流和坏死组织清除术已成为包裹性坏死(WON)患者的标准治疗方法。通过大口径全层金属支架(LAMS)进行内镜治疗在胰腺液体积聚的管理中已显示出成效,但关于该治疗特定并发症的数据较少。我们报告了一例在放置LAMS和进行坏死组织清除术后发生感染性WON并伴有真菌血症的病例。此外,还提供了对当前相关研究的系统文献综述。

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本文引用的文献

1
Lumen Apposing Metal Stents (LAMSs) for Drainage of Pancreatic and Gallbladder Collections: A Meta-analysis.腔内置入金属支架(LAMS)引流胰腺和胆囊积液:荟萃分析。
J Clin Gastroenterol. 2018 Oct;52(9):835-844. doi: 10.1097/MCG.0000000000000934.
2
Endoscopic "step-up approach" using a dedicated biflanged metal stent reduces the need for direct necrosectomy in walled-off necrosis (with videos).内镜下“逐步升级方法”使用专用双喇叭形金属支架可减少隔离性坏死(带视频)直接坏死清除术的需要。
Gastrointest Endosc. 2017 Jun;85(6):1243-1252. doi: 10.1016/j.gie.2016.10.037. Epub 2016 Nov 11.
3
Lumen-apposing metal stents for pancreatic fluid collection drainage: may not be business as usual?
用于胰液积聚引流的管腔贴合金属支架:情况可能并非一如既往?
Gut. 2017 Aug;66(8):1530. doi: 10.1136/gutjnl-2016-313187. Epub 2016 Nov 4.
4
Natural History After Acute Necrotizing Pancreatitis: a Large US Tertiary Care Experience.急性坏死性胰腺炎后的自然病程:美国一家大型三级医疗中心的经验
J Gastrointest Surg. 2016 Nov;20(11):1844-1853. doi: 10.1007/s11605-016-3264-2. Epub 2016 Sep 12.
5
Lumen-apposing metal stents (LAMS) for pancreatic fluid collection (PFC) drainage: may not be business as usual.用于胰液积聚(PFC)引流的管腔对接金属支架(LAMS):可能并非一如既往。
Gut. 2017 Dec;66(12):2054-2056. doi: 10.1136/gutjnl-2016-312812. Epub 2016 Aug 31.
6
Fully covered self-expanding metal stents versus lumen-apposing fully covered self-expanding metal stent versus plastic stents for endoscopic drainage of pancreatic walled-off necrosis: clinical outcomes and success.完全覆膜自膨式金属支架与 lumen-apposing 完全覆膜自膨式金属支架与塑料支架用于内镜引流胰腺包裹性坏死:临床结局和成功率。
Gastrointest Endosc. 2017 Apr;85(4):758-765. doi: 10.1016/j.gie.2016.08.014. Epub 2016 Aug 24.
7
Small Intestinal Angioectasia: Characterization, Risk Factors, and Rebleeding.小肠血管扩张症:特征、危险因素及再出血
J Clin Gastroenterol. 2017 Sep;51(8):720-727. doi: 10.1097/MCG.0000000000000663.
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Fungal Infections in Patients With Walled-off Pancreatic Necrosis.包裹性胰腺坏死患者的真菌感染
Pancreas. 2016 Nov;45(10):1447-1451. doi: 10.1097/MPA.0000000000000675.
9
Lumen-apposing metal stents for drainage of pancreatic fluid collections: When and for whom?腔内置入金属支架治疗胰腺液体积聚:何时及针对哪些患者?
Dig Endosc. 2017 Jan;29(1):83-90. doi: 10.1111/den.12681. Epub 2016 Jun 15.
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Endoscopic Therapy With Lumen-apposing Metal Stents Is Safe and Effective for Patients With Pancreatic Walled-off Necrosis.内镜下置放吻合金属支架治疗胰腺假性囊肿安全有效。
Clin Gastroenterol Hepatol. 2016 Dec;14(12):1797-1803. doi: 10.1016/j.cgh.2016.05.011. Epub 2016 May 14.